Viral & Parasitic infections

Question 1

Nucleoside analogs- drugs

Answer 1

acyclovir, valcyclovir, ribvirin

Question 2

Nucleoside analogs- mechanism of action

Answer 2

Termination of viral DNA replication

Question 3

Nucleoside analogs- spectrum of activity

Answer 3

Herpes
Epstein Barr
varicella-zoster

Question 4

Nucleoside analogs- contraindicaitions & adverse effects

Answer 4

N/V/D

HA

Question 5

Protease inhibitors- drugs

Answer 5

indiavir, saquinavir

Question 6

Protease inhibitors- mech of action

Answer 6

Inhibits protease- immature virus formation

Question 7

Protease inhibitors- spectrum

Answer 7

HIV

Question 8

Protease inhibitors- Adverse effects

Answer 8

Kidney stones, GI, HA,

Question 9

Amantadine- indication

Answer 9

Influenza A

Question 10

Amantadie- Mech of action

Answer 10

prevents virus from entering cells

Question 11

Interferon- mech of action

Answer 11

viral protien synthesis

Question 12

Interferon- Spectrum

Answer 12

Hep B & C

HPV

Question 13

Oseltamivir

Answer 13

Tamiflu- Influenza A

Question 14

Oseltamivir- Mech of action

Answer 14

Inhibition of viral enzyme

Question 15

Lindane

Answer 15

Tx of lice, scabies & crabs
Contraindicatins: hypersensativity, seizure disorders
Adverse effects: arrythmia, ataxia, dizziness, HA, seizure, pruitis

Question 16

Permethrin

Answer 16

Headlice, scabies & nits

Adverse effects: pruitis, erythema, rash

Question 17

Pyrethrins

Answer 17

Head, body & pubic lice

Question 18

Metronidazole

Answer 18

Flagyl- amebic, protozoal and anaerobic bacteria (trichamonas, giardia)

Question 19

Mebendazole

Answer 19

nematodes- whipworm, pinworm, hookworm