Viral Oncogenes Flashcards
Adenovirus
Types 2,5,12
Hepadnavirus
Hepatitis B virus
Tumor: Hepatocellular carcinoma
Cofactors: Aflatoxin, alcohol, smoking
Herpesvirus
Epstein-Barr virus, KSHV
Tumor: Burkitt’s lymphoma, Nasopharyngeal carcinoma, Hodgkin’s lymphoma, gastric carcinoma, Kaposi’s sarcoma (AIDS)
Cofactors: Malaria, immunodeficiency, Nitrosamines, genetic
Flavivirus
Hepatitis C virus
Tumor: Hepatocellular carcinoma
Cofactor: Aflatoxin
Papillomaviruses
HPV16,18,31,33,35,39
Tumor: Anogenital cancers, upper airway cancers, skin cancer
Cofactors: smoking, oral contraceptives, genetic disorder
Polyomavirus
MCV, BK,JC, SV40
Tumor: Merkel cell cancer
Cofactors: UV, immunosuppression
Retroviruses
HTLV-1,2
Tumor: ATL