Viral Lesions Flashcards

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1
Q

What is the most common cause of Infectious Exanthems?

A

Viral

Common culprit: HPV 6 (Parvovirus)

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1
Q

Generalized cutaneous eruption secondary due to an infection

Can be viral, bacterial, rickettsial, parasitic (Viral most common)

Distribution typically generalized

Age <20 years

Prodrome:
Fever
Malaise
NVD
Coryza
Headache
Abdominal pain

A

Infectious Exanthems

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2
Q

6 months to 4 years

High fever

No rash

Then, as fever subsides, rash develops

Morphology: Diffuse erythema, Macular morbilliform, Vesicular eruptions

A

Roseola infantum

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3
Q

Hyperkeratotic lesions

Verruca vulgaris and verruca plantaris

Caused by HPV

Transmission is skin-to-skin contact

Duration: Often persist for several years if not treated

A

Verrucae

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4
Q

What is the common wart called?

A

Verruca Vulgaris

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5
Q

What is the causative agent of the common wart?

A

HPV

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6
Q

Often persists several years if not treated

Firm papules 1-10mm (rarely larger)

Hyperkeratotic, clefted surface with vegetations

Characteristic red or brown dots, often called “seeds” (the “seed” = capillaries)

A

Verruca Vulgaris

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7
Q

Plantar warts are also known as what?

A

Verruca Plantaris

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8
Q

What is the causative agent of the plantar wart?

A

HPV

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9
Q

Caused by HPV

Often persists several years if not treated

Early small, shiny, sharply marginated papule localized to feet

Plaque with rough hyperkeratotic surface studded with brown-black dots

A

Verruca Plantaris

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10
Q

What are some treatment options for Verruca?

A

Salicyclic acid and lactic acid in collodion
Imiquimod cream 5%
Podofilox 0.5% solution and gel
Co2 laser
Cryosurgery – commonly used
Hyperthermia for verruca plantaris
Duct tape

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11
Q

Self-limited epidermal viral infection

Presents as a round or oval lesions that is umbilicated

Occurs in children and sexually active adults

Skin to skin contact transmission

Persists up to 6 months then undergoes spontaneous regression

Can be see in HIV infected individuals (most commonly on the face)

A

Molluscum Contagiosum

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12
Q

Papules or nodules

Pearly white or skin-colored

Round, oval, or hemispherical

Characteristic umbilication - Central spot

Can be isolated lesion or multiple

Localized or scattered

Can even present as confluent mosaic plaques

A

Molluscum Contagiosum

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13
Q

What are some treatment options for molluscum contagiosum?

A

Supportive - Typically resolve on their own (treatment usually done for cosmetic reasons)

Imiquimod 5%

Tretinoin (Retin-A)

Curettage

cryosurgery

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14
Q

Caused by HPV 6 and 11

Called “genital warts”

Soft, fleshy growths, “cauliflower” lesions that arise from the vulva, vagina, cervix, urethral meatus, perineum and anus (can also be found on the tongue or oral cavity)

Single or multiple

Can be dormant for years

Common in young sexually active adults - Spread by direct, skin to skin contact

There are four clinical types

A

Condyloma Acuminatum

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15
Q

What are the four clinical types of Condyloma Acuminatum?

A

Small popular
Cauliflower-floret lesions
Keratotic warts
Flat-topped papules/plaques

16
Q

Cauliflower-like skin lesions

Hyperkeratic papules to plaques

flesh- colored, pink, red, tan, or brown

Smooth surface or jagged growths

Lesions can be solitary, scattered and isolated

A

Condyloma Acuminatum

17
Q

What is helpful in visualizing condyloma acuminatum lesions on the cervix and anus?

A

acetic acid

18
Q

What are some treatment options for patients with condyloma acuminatum?

A

May resolve spontaneously
Trichloroacetic acid solution
Imiquimod 5% cream
Podofilox 0.5% solution and gel
TCA or BCA 80-90%
Laser removal
Cryosurgery with liquid nitrogen
Excision using scalpel

19
Q

Grouped small vesicles on erythematous base

Superficial lesion- rupture early and erosion

Crust and heal

A

Herpes Simplex

20
Q

What is the causative agent in Varicella-Zoster?

A

Causative agent 🡪 HHV-3

21
Q

First lesion vesicle on an erythematous base - “dewdrop on rose petal”

Crops of lesions

Papule-vesicle-erosion-crust

A

Varicella

22
Q

Latent in dorsal spinal ganglia after primary varicella infection

Also HSV-3

When immunity declines, reactivates, and re-erupts in a dermatomal pattern

Painful

Prodromal symptoms of burning and tingling

Vesicular eruption in a dermatome pattern - Localized to a single spinal nerve, Linear type pattern along a dermatome
**Won’t cross the midline

A

Zoster