Acneiform Lesions Flashcards

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1
Q

Inflammation of the pilosebaceous units of certain body areas

Face, chest, back

Manifests itself as comedones, papulopustules, or nodules/cysts

Age of onset- puberty

A

Acne Vulgaris

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2
Q

What are the key factors for the development of acne vulgaris?

A

Key factors are follicular keratinization, androgens, and
Propionibacterium acnes

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3
Q

What are some contributary factors for the development of acne vulgaris?

A

Contributary factors are acnegenic mineral oils, drugs, emotional
stress, occlusion and pressure on the skin

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4
Q

excess skin cells or build up on the skin

A

Follicular keratinization

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5
Q

this bacteria lies deep within the pore and is anaerobic; over time it breaks down the heavy oil in the sebaceous gland, which causes inflammation which results in pimples and cysts

A

Propionibacterium acnes:

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6
Q

Comedones: Open (blackheads), Closed (whiteheads)

Papules and papulopustules

Nodules or cysts: 1-4 cm in diameter, “Undergrounders”

A

Acne Vulgaris

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7
Q

What is the treatment for mild acne vulgaris?

A

OTC:

Topical antibiotics (Clindamycin and Erythromycin

Benzoyl peroxide gels (2%, 5%, or 10%)

Topical retinoids

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8
Q

What is the treatment for moderate acne vulgaris?

A

Add “cyclines” 🡪 Minocycline is good for acne
Tetracycline an option

Women – add high dose estrogens + progesterone + antiandrogens

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9
Q

What is the treatment for severe acne vulgaris?

A

Accutane (Isotretinoin) is an option – most effective for cystic acne (Managed by a dermatologist, someone who is accredited)

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10
Q

Common chronic inflammatory acneiform disorder of the facial
pilosebaceous units, increased reactivity of capillaries leading to flushing and telangiectasia

Age of onset - 30-50 years with a peak incident between 40 and 50 years

Predominately in females

A

Rosacea

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11
Q

Rosacea is also called what?

A

adult acne

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12
Q

What stage of Rosacea is described below?

Persistent erythema with telangiectases

A

Stage I

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13
Q

What stage of Rosacea is described below?

Persistent erythema, telangiectases, papules, tiny pustules

A

Stage II

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14
Q

What stage of Rosacea is described below?

Persistent deep erythema, dense telangiectases, papules, pustules, nodules

Rarely persistent “solid” edema of the central part of the face

A

Stage III

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15
Q

Describe the early presentation of Rosacea

A

Capillaries undergo continual inflammation and dilation

Pathognomonic flushing (red face)

Tiny papules and papulopustules - Pustule often small (<1mm) and
on the apex of the papule

No comedones

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16
Q

Describe the late presentation of Rosacea

A

Red facies and dusky-red papules and nodules

Scattered, discrete lesions

Telangiectases

Marked sebaceous hyperplasia and lymphedema in chronic rosacea, causing disfigurement of the nose, forehead, eyelids, ears, and chin

17
Q

What is the treatment for Rosacea?

A

Topical - Metronidazole gel or cream

Systemic - Minocycline or Doxycycline; Metronidazole

18
Q

Chronic, suppurative, often cicatrical disease of apocrine gland-bearing skin in the axillae, anogenital region, and the scalp (rare)

Inflammatory changes to apocrine glands

Unique double comedones

Age of onset: puberty to climacteric

More common in females than males

More common in obesity and diabetes

Etiology is unknown

A

Hidradenitis Suppurativa

19
Q

Intermittent pain and marked point tenderness related to abscess formation in axillae and/or anogenital area

Inflammatory nodules/abscesses of axillae, buttocks, inguinal region

A

Hidradenitis Suppurativa

20
Q

Initial lesion - Very tender, Red, inflammatory nodule/abscess that may resolve or drain purulent/seropurulent material

Unique double comedones – double blackheads

Later lesions - pus drains from opening of abscess and sinus tracts

A

Hidradenitis Suppurativa

21
Q

What are the treatment options for Hidradenitis Suppurativa?

A

Supportive/Watchful Waiting - some can resolve on their own

Intralesional glucocorticoids

Surgery

Oral antibiotics - Tetracycline, Erythromycin, Minocycline

isotretinoin