Viral infection Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Viral warts are caused by what family of virus?

A

Human papillomavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

HPV subtypes:

a) common warts
b) plane warts
c) genital warts

A

a) 1, 2 and 4
b) 2
c) 6, 11, 16 and 18

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is spontaneous resolution of a viral wart often preceded by?

A

Blackening within the wart due to capillary thrombosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Infection with which HPV serotypes predisposes to cervical cancer?

A

16 and 18

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Treatment options for viral warts (5)

A
12 weeks daily application of salicylic acid "wart paint"
Cryotherapy
Curettage and cautery
Podophyllotoxin
Immunomodulation e.g. imiquimod
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Natural course of varicella

A

Malaise
Papules –> clear vesicles on a pink base
Vesicles become pustules
Lesions crust then clear, leaving white depressed scars

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Management of varicella (2)

A

Active Rx rarely required- topical calamine lotion is usful

Antivirals should be reserved for severe attacks and immunocompromised people (prophylactically if exposed)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Pathophysiology of herpes zoster

A

Reactivation of dormant herpes varicella-zoster virus in the dorsal (sensory) root ganglion since an earlier episode of chickenpox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Presentation of herpes zoster (2)

A

Neuralgic pain and vesicles in a dermatomal pattern

Initial pain is sometimes taken for an emergency e.g. MI, acute appendicitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Complications of herpes zoster (3)

A

Secondary bacterial infection
Opthalmic zoster can cause corneal ulcers (involvement of tip of nose indicates this)
Post-herpetic neuralgia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Treatment of herpes zoster (2)

A

If diagnosed early, antivirals are of benefit

Vaccination with live attenuated vaccine reduces incidence of zoster and post-herpetic neuralgia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the two types of herpes simplex virus and where do they generally cause lesions?

A

HSV I- usually extragenital

HSV II- usually genital lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How does primary herpes simplex virus manifest in children?

A

Acute gingivostomatitis with malaise, fever, lethargy, cervical lymphadenopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is herpetic whitlow?

A

Direct inoculation of herpes simplex virus onto finger causing fluid filled blister

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How does primary herpes simplex virus II infection manifest?

A

Painful anogenital blisters which rapidly ulcerate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

examples of triggers for reactivation of herpes simplex? (5)

A

Menstruation
stress
illness
UV radiation

17
Q

Complications of herpes simplex (5)

A
Disseminated herpes simplex (causing severe systemic illness)
Herpes encephalitis or meningitis
Eczema herpeticum
Dendritic ulcers
Erythema multiforme
18
Q

Treatment of herpes simplex

A

Topical or oral aciclovir

19
Q

Pearly umbilicated papules caused by infection with a common pox virus

A

Molluscum contagiosum

20
Q

Management options: molluscum contagiosum (4)

A

Cryotherapy, C + C, salicylic acid wart paint, topical imiquimod

21
Q

Most common HIV-associated malignancy, caused by herpesvirus 8

A

Kaposi sarcoma

22
Q

Appearance of Kaposi sarcoma?

A

Multiple purplish patches/nodules

23
Q

Other skin changes in AIDS (5)

A
Seborrhoeic eczema
Florid, unusually extensive or atypical common infections e.g. candida, tinea, herpes simplex, scabies, warts
Hairy leucoplacia
Dry skin, pruritus
Drug eruptions
24
Q

Causative viruses:

a) herpangina
b) hand foot and mouth disease
c) erythema infectiousum

A

a) group A coxsackie viruses
b) coxsackie A16
c) parvovirus B19

25
Q

Child with fever, severe sore throat covered in many vesicles/ulcers?

A

Herpangina

26
Q

Slapped cheek erythema indicates?

A

Erythema infectiosum