Exam Flashcards
Management of basal cell papilloma/seborrhoeic keratosis
Cryotherapy
Why are keratoacanthomas often excised?
Difficulty to distinguish between a SCC
Difference between a papule and a nodule?
Papule is less than 0.5cm
both are solid raised lesions
Staph infection around/within a hair follicle
Furnuncle
Functions of skin:
a) Langerhans cells
b) Merkel cells
a) Antigen presenting cells of the skin
b) light touch mechanoreceptors
Four layers of epidermis from deep –> superficial
Basal
Prickle
Granular
Stratum corneum
Pearly lesion with a rolled edge and telangiectasia
Basal cell carcinoma
BCC treatment options? (4)
Excision
Moh’s micrographic surgery
Cryotherapy
Imiquimod
What pattern of sun exposure broadly predisposes to a) BCC b) SCC?
a) intense, intermittent e.g. severe episodes of sunburn
b) chronic sun exposure e.g. an outside occupation like a farmer
Squamous cell carcinoma in situ is also known as…
Bowen’s disease
SCC precursor lesions? (2)
Actinic keratoses
Bowen’s disease
Patch of malignant melanocytes proliferating radially along the dermo-epidermal junction
Lentigo maligna
Commonest melanoma type?
Superficial spreading
Melanoma subtypes:
a) invasive growth from outset
b) seen on sole/palm/subungual
c) radially prolferating along the DEJ
d) diffuse blue/black patch on lower back/buttocks of a child
a) nodular
b) acral
d) lentigo maligna
d) Mongolian blue spot (congenital)
ABCDE criteria for assessing melanoctyic lesions?
Asymmetry Border (irregular) Colour (heterogenous) Diameter (>6mm) Evolution over time
Blistering skin disease:
IgG deposition in a “chicken-wire” pattern around cells within the epidermis
Pemphigus
Blistering skin disease:
linear IgG deposition along the basement membrane
Pemphigoid