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GI - Week 2 > Viral hepatitis > Flashcards

Viral hepatitis Flashcards

1
Q

Hepatitis A belongs to this viral family

A

Picornavirus

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2
Q

This hepatitis virus belongs to the Picornavirus family

A

Hepatitis A

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3
Q

What is the route of transmission for Hepatitis A?

A

Fecal-oral
epidemics frequent

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4
Q

Do most cases of Hepatitis A resolve?

A

Yes - almost always a self-limited infection

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5
Q

Is there chronic Hepatitis A?

A

No

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6
Q

Rash, leukocytoclastic vasculitis, arthralgias, and glomerulonephritis are extrahepatic symptoms of these two hepatitis viruses

A

Hepatitis A and B

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7
Q

This is used to diagnose active infection with Hepatitis A

A

IgM

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8
Q

Hepatitis B belongs to this viral family

A

Hepadnavirus

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9
Q

This hepatitis virus belongs to the Hepadnavirus family

A

Hepatitis B

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10
Q

This hepatitis virus is considered highly infectious

A

Hepatitis B

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11
Q

This hepatitis virus is the most common cause of chronic liver disease and hepatocellular carcinoma

A

Hepatitis B

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12
Q

This hepatitis virus is an endemic in SE Asia, China, Africa

A

Hepatitis B

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13
Q

Perinatal transmission may occur with these two hepatitis viruses

A

Hepatitis B and C

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14
Q

Is there chronic Hepatitis B?

A

Yes - is age dependent (95% of perinatal infections become chronic)

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15
Q

Is perinatal infection or adult infection with Hepatitis B more likely to become chronic?

A

Perinatal
95% become chronic

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16
Q

Are most cases of Hepatitis B asymptomatic?

A

Yes (70%)

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17
Q

25% of patients with chronic hepatitis with this virus develop cirrhosis with risk of hepatocellular carcinoma

A

Hepatitis B

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18
Q

This serologic marker for Hepatitis B indicates transmissible infection

A

sAg (surface Ag)

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19
Q

This serologic marker for Hepatitis B is best for acute infection (window period)

A

IgM anti HepBc (core Ag)

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20
Q

This serologic marker for Hepatitis B indicates immunity

A

Anti-sAg

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21
Q

This serologic marker for Hepatitis B increases with increasing transmissibility

22
Q

This serologic marker for Hepatitis B correlates with decreased viremia/transmission

23
Q

In Hepatitis B serology, sAg indicates this

A

Transmissible infection

24
Q

In Hepatitis B serology, IgM anti HepBc indicates this

A

Acute infection (window period)

25
Q

In Hepatitis B serology, anti-sAg indicates this

26
Q

In Hepatitis B serology, eAg indicates this

A

Transmissibility
(increases with increasing transmissibility)

27
Q

In Hepatitis B serology, eAb indicates this

A

Correlates with decreased viremia/transmission

28
Q

This test is used to assess treatment or risk of progression of hepatitis B

29
Q

Hepatitis C belong to this viral family

A

Flavivirus

30
Q

This hepatitis virus belongs to the flavivirus family

A

Hepatitis C

31
Q

Transmission of Hepatitis C is this

A

Parenteral
(IV drug use, occupation exposure, transfusion, partuition, sexual)

32
Q

This is the most common cause of chronic viral hepatitis

A

Hepatitis C

33
Q

Is there chronic infection with Hepatitis C?

A

Yes - most infections become chronic and persistent

34
Q

Do acute infections with Hepatitis C cause severe disease?

35
Q

In Hepatitis C with recovery, is PCR positive or negative?

36
Q

Is Hepatitis C PCR positive in chronic infection?

A

Yes - remains positive

37
Q

In Hepatitis C, disease activity tends to fluctuate, and correlates with this

38
Q

Life cycle of this hepatitis virus depends on HepB presence

A

Hepatitis D

39
Q

Life cycle of Hepatitis D depends on the presence of this

40
Q

Transmission of Hepatitis D is this

A

Parenteral

41
Q

This hepatitis virus is enterically transmitted and zoonotic

A

Hepatitis E

42
Q

Infection with this hepatitis virus is associated with travel to Asia, India, Africa
Infection is self-limited

A

Hepatitis E

43
Q

Is there chronic Hepatitis E infection?

44
Q

Hepatitis E has risk of fulminant hepatitis in this patient population

A

Pregnant women

45
Q

The average incubation period of Hepatitis E is this many days

46
Q

Does Hepatitis E illness severity increase or decrease with age?

47
Q

Is there portal lymphocyte inflammation in viral hepatitis?

A

Yes
(extension into limiting plate = interface hepatitis)

48
Q

Are acidophil bodies and Kupffer cell clusters seen in viral hepatitis?

49
Q

Morphology of this hepatitis virus has classic micronodular cirrhosis

A

Hepatitis C

50
Q

Does HepC antibodies or PCR show exposure?

A

Antibodies

51
Q

Does HepC antibodies or PCR show presence of virus?

52
Q

These three hepatitis viruses can have chronic infections

GI - Week 2 (12 decks)

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