Viral Hepatitis Flashcards
An inflammation of the liver that is caused by a variety of infectious viruses and noninfectious agents leading to a range of health problems.
Hepatitis
The yellowing of skin, mucous membrane, and the sclera of the eyes.
Jaundice
What are the modes of transmission of the Hepatitis A Virus?
Fecal-oral route
Shellfish from sewage-contaminated water
What virus group is the HAV?
Picornavirus
Which age group is most likely to develop jaundice in HAV?
> 14 years - 70%-80% (adults)
The HAV is released as what?
Bile
Hepatitis A does not have a chronic form of disease.
True
Hepatitis virus with resistance to ether, low pH, freezing/moderate temperature.
Hepatitis B
How does the Hepatitis B Virus enter the cell?
Endocytosis
The following are non-enevloped hepatitis viruses EXCEPT:
HAV
HEV
HCV
HDV
HCV
What serves as the template for viral replication that happens inside the nucleus in Hepatitis B Virus?
covalently closed circular DNA (cccDNA)
The HBV starts to replicate within how many days of its acquisition?
3 days
Age group most likely to have Chronic hepatitis in HBV?
<5 years — 30%-90%
What is the concentration of HBV in blood, serum, and wound exudates?
High
Concentration of HBV in semen, saliva, anniotic fluid, vaginal, and menstrual secretions.
Moderate
WHO estimates that 80% of all cases of this can be attributed to chronic HBV infections and may induce it by promoting continued liver repair and cell growth in response to tissue damage or by integrating into the host chromosome and stimulating growth directly.
Primary Hepatocellular Carcinoma
Specific treatment for Acute Hepatitis B.
None
Hepatitis virus closely related to the general flavivirus and pestivirus.
Hepatitis C
Chronic Hepatitis C does not have a risk of cirrhosis.
False
Laboratory diagnosis that detects viral genome in patient’s serum.
PCR
The only known effective treatment for HCV.
Recombinant inferon-alpha
Defective virus that required HBV as a helper virus in order to replicate.
Hepatitis D
What does the replication of delta agent in Hepatitis V result in?
Cytotoxicity and Liver damage
The HEV resolves on its own without treatment.
True
This is a type of infection where someone with chronic Hepatitis B becomes infected with Hepatitis D
Superinfection
This is a type of infection where someone becomes infected with Hepatitis B and Hepatitis D at the same time
Coinfection
This is an inflammation of the liver that is caused by a variety of infectious viruses and noninfectious agents leading to a range of health problems, some of which can be fatal.
Liver cirrhosis
