Viral Hepatitis

Question 1

An inflammation of the liver that is caused by a variety of infectious viruses and noninfectious agents leading to a range of health problems.

Answer 1

Hepatitis

Question 2

The yellowing of skin, mucous membrane, and the sclera of the eyes.

Answer 2

Jaundice

Question 3

What are the modes of transmission of the Hepatitis A Virus?

Answer 3

Fecal-oral route
Shellfish from sewage-contaminated water

Question 4

What virus group is the HAV?

Answer 4

Picornavirus

Question 5

Which age group is most likely to develop jaundice in HAV?

Answer 5

> 14 years - 70%-80% (adults)

Question 6

The HAV is released as what?

Answer 6

Bile

Question 7

Hepatitis A does not have a chronic form of disease.

Answer 7

True

Question 8

Hepatitis virus with resistance to ether, low pH, freezing/moderate temperature.

Answer 8

Hepatitis B

Question 9

How does the Hepatitis B Virus enter the cell?

Answer 9

Endocytosis

Question 10

The following are non-enevloped hepatitis viruses EXCEPT:

HAV
HEV
HCV
HDV

Answer 10

HCV

Question 11

What serves as the template for viral replication that happens inside the nucleus in Hepatitis B Virus?

Answer 11

covalently closed circular DNA (cccDNA)

Question 12

The HBV starts to replicate within how many days of its acquisition?

Answer 12

3 days

Question 13

Age group most likely to have Chronic hepatitis in HBV?

Answer 13

<5 years — 30%-90%

Question 14

What is the concentration of HBV in blood, serum, and wound exudates?

Answer 14

High

Question 15

Concentration of HBV in semen, saliva, anniotic fluid, vaginal, and menstrual secretions.

Answer 15

Moderate

Question 16

WHO estimates that 80% of all cases of this can be attributed to chronic HBV infections and may induce it by promoting continued liver repair and cell growth in response to tissue damage or by integrating into the host chromosome and stimulating growth directly.

Answer 16

Primary Hepatocellular Carcinoma

Question 17

Specific treatment for Acute Hepatitis B.

Answer 17

None

Question 18

Hepatitis virus closely related to the general flavivirus and pestivirus.

Answer 18

Hepatitis C

Question 19

Chronic Hepatitis C does not have a risk of cirrhosis.

Answer 19

False

Question 20

Laboratory diagnosis that detects viral genome in patient’s serum.

Answer 20

PCR

Question 21

The only known effective treatment for HCV.

Answer 21

Recombinant inferon-alpha

Question 22

Defective virus that required HBV as a helper virus in order to replicate.

Answer 22

Hepatitis D

Question 23

What does the replication of delta agent in Hepatitis V result in?

Answer 23

Cytotoxicity and Liver damage

Question 24

The HEV resolves on its own without treatment.

Answer 24

True

Question 25

This is a type of infection where someone with chronic Hepatitis B becomes infected with Hepatitis D

Answer 25

Superinfection

Question 26

This is a type of infection where someone becomes infected with Hepatitis B and Hepatitis D at the same time

Answer 26

Coinfection

Question 27

This is an inflammation of the liver that is caused by a variety of infectious viruses and noninfectious agents leading to a range of health problems, some of which can be fatal.

Answer 27

Liver cirrhosis