Viral Hepatitis Flashcards

1
Q

How is hepatitis A spread?

A

Faeco-oral
Poor hygiene/overcrowding

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2
Q

Hepatitis A is associated with gay men having sex and IV drug users. True/False?

A

True

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3
Q

Does hepatitis A produce chronic infection?

A

No

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4
Q

Which age group has peak incidence of symptoms associated with hepatitis A?

A

Older children - young adults

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5
Q

How is hepatitis A confirmed in the lab?

A

Serology (clotted blood)
Hep A IgM

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6
Q

Hepatitis E is more common than hepatitis A in the UK. True/False?

A

True

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7
Q

How is hepatitis E spread?

A

Faeco-oral
Zoonosis
Person-person in immunocompromised/tropics

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8
Q

Hepatitis D is only found with hepatitis B infection. True/False?

A

True
Exacerbates hepatitis B infection

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9
Q

How is hepatitis B spread?

A

Blood-blood
Sex

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10
Q

Hep B s Ag is present in all hepatitis B -infected individuals. True/False?

A

True

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11
Q

HBsAg present for 4 months indicates chronic infection. True/False?

A

False
Present for > 6 months in chronic infection

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12
Q

Which hepatitis B markers are usually present in highly infectious individuals?

A

Hep B e Ag
Hep B virus DNA

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13
Q

Presence of anti-Hep B IgG indicates acute infection. True/False?

A

False
Presence of anti-Hep B IgM indicates acute infection

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14
Q

How is hepatitis C spread?

A

Blood-blood
Sex (although not as easily as hepatitis B)

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15
Q

Are antivirals given in acute hepatitis?

A

No

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16
Q

Liver cancer is a contraindication for hepatitis treatment. True/False?

A

True

17
Q

List antivirals used to treat chronic hepatitis infection

A

Adefovir
Entecavir
Tenofovir

18
Q

Hep B serology:
HBsAg?

A

Infectious individual
6+ months chronic infection

19
Q

Hep B serology:
HBeAg?

A

Highly infectious individual

20
Q

Hep B serology:
Hep B IgM?

A

Recently infected case

21
Q

Hep B serology:
Anti-HBs?

A

Present in immunity
(Vaccine or past infection)

22
Q

Hep B PCR:
Hep B virus DNA

A

Highly infectious individual

23
Q

Hep B serology:
HBcAb?

A

Implies past or current infection

24
Q

Hep B serology:
HBsAb?

A

Implies vaccination or past or current infection