viral clinical course Flashcards

1
Q

HSV-1

A

gingivostomatitis/cold sores, encephalitis with focal temporal lesions, neonatal herpes, keratoconjunctivitis

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2
Q

HSV-2

A

painful genital vesicles, encephalitis with focal temporal lesions, neonatal herpes, keratoconjunctivitis

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3
Q

VZV

A

chicken pox- asynchronous vesicular rash
shingles- painful vesicles in a dermatomal distribution
reactivation of VZV can cause Ramsay Hunt syndrome (Bell’s palsy, ear pain, vesicles in ear canal)

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4
Q

CMV

A

mono
in immunocompromised- retinitis, interstitial pneumonitis, GI disease/esophagitis/colitis
congenital- fetal microcephaly and periventricular calcifications

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5
Q

HHV-6/7

A

roseola- fever for 5 days followed by a lacy body rash that spares the face

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6
Q

EBV

A

mono

Burkitt’s lymphoma, nasopharyngeal carcinoma

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7
Q

HHV-8

A

Kaposi’s sarcoma

dark plaques/nodules on the skin

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8
Q

Molluscum contagiosum

A

flesh colored papule with central umbilication

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9
Q

Variolla

A

small pox- synchronous vesicular rash

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10
Q

HPV

A

serotypes 1-4- cutaneous warts
serotypes 6/11- anogenital warts (condyloma acuminata)
serotypes 16/18- neoplastic (anal, vaginal, vulvar, penile and laryngeal cancers)

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11
Q

Parvovirus B19

A

“slapped cheek” rash, raised indurated facial rash, arthralgia, myocarditis, fetus with severe anemia, heart failure and hydrops fetalis

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12
Q

Yellow Fever

A

jaundice, back pain, black commit, bloody stools

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13
Q

Dengue Fever

A

“breakbone fever”, retro-orbital headache, hemorrhagic shock, debilitating myalgias, thrombocytopenia

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14
Q

Zika Virus

A

fever, itchy rash, arthralgia, conjunctivitis

congenital- microcephaly and fetal demise

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15
Q

Rubella

A

erythematous rash that starts on the face, proceeds to the trunk and does NOT coalesce
congenital- cataracts, heart defects, hearing loss

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16
Q

Measles

A

rubeola
4 C’s- cough, coryza, conjunctivitis, Koplik spots
erythematous rash that starts on the head and progresses downward and can coalesce

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17
Q

Mumps

A

parotitis, orchitis (testes inflammation), pancreatitis

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18
Q

Ebola

A

flu-like, fatigue, vomitting, diarrhea, bloody stools (can cause massive hemorrhage and shock)

19
Q

JC virus

A

progressive multifocal leukoencephalopathy

neurological symptoms

20
Q

BK virus

A

kidney disease

21
Q

Poliovirus

A

flaccid paralysis (asymmetric with NO sensory loss), aseptic meningitis

22
Q

West Nile virus

A

myalgias, stiff neck, summer encephalitis, muscle weakness

weakness = a distinguishing characteristic in patients with acute viral encephalitis

23
Q

Chikungunya

A

fever and joint pain

24
Q

Rabies virus

A

flu-like, then neurological symptoms of hydrophobia and hallucinations

25
Q

Lymphocytic choriomeningitis virus

A

2 phases
- fever, headache, muscle pain, n/v, sore throat, parotid pain
- aseptic meningitis or encephalitis
congenital- spontaneous abortions, brain abnormalities, optic abnormalities

26
Q

Influenza

A

younger children- bronchiolitis, croup, otitis media

complicated by Reye syndrome or Guillan-Barre syndrome

27
Q

Adenovirus

A

acute respiratory disease, pharyjgoconjunctival fever (“pool fever”), acute hemorrhagic cystitis in boys 5-15 (dysuria, hematuria), myocarditis

28
Q

Coxsackie A

A

hand foot and mouth disease, acute hemorrhagic conjunctivitis, aseptic meningitis, upper respiratory disease

29
Q

Coxsackie B

A

organ involvement, Devil’s grip (Bornholm disease), pleurodynia, myocarditis, pericarditis, dilated cardiomyopathy, hepatitis

30
Q

Echovirus

A

aseptic meningitis, neonatal sepsis, myocarditis

31
Q

Rhinovirus

A

common cold- sore throat, rhinnorhea, nasal congestion, cough, mild fever

32
Q

Coronavirus

A

common cold, SARS, MERS

33
Q

RSV

A

common cold

infants- bronchiolitis, necrosis of bronchioles, atypical pneumonia

34
Q

Parainfluenza

A

croup, subglottal swelling, hoarse barking cough

35
Q

Human metapneumovirus

A

common cold, similar to RSV

36
Q

Hantavirus

A

hemorrhagic fever with renal syndrome

pulmonary syndrome- SOB

37
Q

Norwalk virus

A

n/v, watery diarrhea

38
Q

Rotavirus

A

n/v, watery diarrhea

39
Q

Hepatitis A

A

jaundice, often asymptomatic, fever, nausea, fatigue, anorexia

40
Q

Hepatitis E

A

jaundice, fever, nausea, fatigue, anorexia

41
Q

Hepatitis B

A

jaundice, fever, nausea, fatigue, anorexia, hepatocellular carcinoma

42
Q

Hepatitis C

A

NO jaundice, fever, nausea, fatigue, anorexia, cirrhosis, liver cancer

43
Q

Hepatitis D

A

more severe complications and disease of Hepatitis B