VI. Endocrine

Question 1

Hormone responsible for follicle development and estrogen secretion in women while seminiferous tubule development in men

Answer 1

Follicle Stimulating Hormone (FSH)

Question 2

Hormone responsible for ovulation and maintenance of corpus luteum in women while leydig cell development in men

Answer 2

Luteinizing Hormone (LH)

Question 3

A hormone with a circadian rhythm, peaking at 6am and approaches nadir at midnight

Answer 3

Adrenocorticotrophic Hormone (ACTH)

Question 4

Hormone responsible for bone aging and stimulating IGF-1

Answer 4

Growth Hormone (GH)

Question 5

Medical treatment for Acromegaly

Answer 5

Somatostatin Analogues

Question 6

Hormone which peaks at 4-6am during REM

Answer 6

Prolactin

Question 7

DOC for hyperprolactinemia

Answer 7

Dopamine Agonists (Cabergoline, Bromocriptine)

Question 8

Most common cause of hypothyroidism

Answer 8

Iodine deficiency

Question 9

A condition characterized by sweating, headaches, palpitations, heart failure, pulmonary edema, arrythmias, and cerebral hemorrhages

Answer 9

Pheochromocytoma

Question 10

DOC for pheochromocytoma

Answer 10

Phenoxybenzamine

Question 11

A condition characterized by Kussmaul’s respiration, fruity breath, lethargy and central brain edema

Answer 11

Diabetic Ketoacidosis

Question 12

Macrovascular complicaitons of DM

Answer 12

PAD, CAD, stroke

Question 13

Microvascular complications of DM

Answer 13

Retinopathy, macular edema, neuropathy, nephropathy

Question 14

A condition characterized by Verner-Morrison syndrome, pancreatic cholera, and WDHA syndrome (watery diarrhea, hypokalemia, achlorhydria)

Answer 14

VIPoma (Tx: correct dehydration and hypokalemia, octreotide)

Question 15

Neoplasia of the parathyroid glands, enteropancreatic tumors, anterior pituitary adenomas, and neuroendocrine tumors with a defect on Chromosome 11q13 which encodes Menin

Answer 15

Multiple Endocrine Neoplasia Type I (Werner’s Syndrome)

Question 16

A condition characterized by medullary thryoid Ca, pheochromocytoma, and hyperparathyroidism

Answer 16

Multiple Endocrine Neoplasia Type 2A

Question 17

A condition characterized by medullary thryoid Ca, pheochromocytoma, mucosal neuromas, intestinal ganglioneuromatosis and marfanoid features

Answer 17

Multiple Endocrine Neoplasia Type 2B

Question 18

The gene that codes for Cu-ATPase pump in Wilson’s Disease

Answer 18

ATP7B gene

Question 19

The lysosomal storage disease with a deficiency in hexosaminidase

Answer 19

Tay-Sach’s disease

Question 20

The lysosomal storage disease with a mutation in alpha glucosidase

Answer 20

Fabry’s disease

Question 21

The lysosomal storage disease with a deficiency in beta galactosidase

Answer 21

Gaucher’s disease

Question 22

The lysosomal storage disease with a deficiency in sphingomyelinase

Answer 22

Niemann Pick’s Disease

Question 23

The glycogen storage disease with a deficiency in G6PD

Answer 23

Von Gierke Disease (Type I)

Question 24

The glycogen storage disease with a deficiency in acid maltase

Answer 24

Pompe Disease (Type II)

Question 25

The glycogen storage disease with a deficiency in glycogen debranching enzyme

Answer 25

Cori Disease (Type III)

Question 26

The glycogen storage disease with a deficiency in muscle phosphorylase

Answer 26

McArdle’s Disease (Type V)