VI. Endocrine Flashcards
Hormone responsible for follicle development and estrogen secretion in women while seminiferous tubule development in men
Follicle Stimulating Hormone (FSH)
Hormone responsible for ovulation and maintenance of corpus luteum in women while leydig cell development in men
Luteinizing Hormone (LH)
A hormone with a circadian rhythm, peaking at 6am and approaches nadir at midnight
Adrenocorticotrophic Hormone (ACTH)
Hormone responsible for bone aging and stimulating IGF-1
Growth Hormone (GH)
Medical treatment for Acromegaly
Somatostatin Analogues
Hormone which peaks at 4-6am during REM
Prolactin
DOC for hyperprolactinemia
Dopamine Agonists (Cabergoline, Bromocriptine)
Most common cause of hypothyroidism
Iodine deficiency
A condition characterized by sweating, headaches, palpitations, heart failure, pulmonary edema, arrythmias, and cerebral hemorrhages
Pheochromocytoma
DOC for pheochromocytoma
Phenoxybenzamine
A condition characterized by Kussmaul’s respiration, fruity breath, lethargy and central brain edema
Diabetic Ketoacidosis
Macrovascular complicaitons of DM
PAD, CAD, stroke
Microvascular complications of DM
Retinopathy, macular edema, neuropathy, nephropathy
A condition characterized by Verner-Morrison syndrome, pancreatic cholera, and WDHA syndrome (watery diarrhea, hypokalemia, achlorhydria)
VIPoma (Tx: correct dehydration and hypokalemia, octreotide)
Neoplasia of the parathyroid glands, enteropancreatic tumors, anterior pituitary adenomas, and neuroendocrine tumors with a defect on Chromosome 11q13 which encodes Menin
Multiple Endocrine Neoplasia Type I (Werner’s Syndrome)
A condition characterized by medullary thryoid Ca, pheochromocytoma, and hyperparathyroidism
Multiple Endocrine Neoplasia Type 2A
A condition characterized by medullary thryoid Ca, pheochromocytoma, mucosal neuromas, intestinal ganglioneuromatosis and marfanoid features
Multiple Endocrine Neoplasia Type 2B
The gene that codes for Cu-ATPase pump in Wilson’s Disease
ATP7B gene
The lysosomal storage disease with a deficiency in hexosaminidase
Tay-Sach’s disease
The lysosomal storage disease with a mutation in alpha glucosidase
Fabry’s disease
The lysosomal storage disease with a deficiency in beta galactosidase
Gaucher’s disease
The lysosomal storage disease with a deficiency in sphingomyelinase
Niemann Pick’s Disease
The glycogen storage disease with a deficiency in G6PD
Von Gierke Disease (Type I)
The glycogen storage disease with a deficiency in acid maltase
Pompe Disease (Type II)
The glycogen storage disease with a deficiency in glycogen debranching enzyme
Cori Disease (Type III)
The glycogen storage disease with a deficiency in muscle phosphorylase
McArdle’s Disease (Type V)
