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BMS242 Cell & Molecular > Vesicular Trafficking II > Flashcards

Vesicular Trafficking II Flashcards

1
Q

How is transport through the secretory pathway mediated

A

coated vesicles and tubules

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2
Q

Mutation in Sec23A

A

cranio-lenticulo-sutural dysplasia, abnormal ER to golgi trafficking

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3
Q

ER in cranio-lenticulo-sutural dysplasia

A

dilated

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4
Q

In cranio-lenticulo-sutural dysplasia what is unaffected

A

binding of mutant SEC23A to liposomes

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5
Q

What is affected in cranio-lenticulo-sutural dysplasia

A

COPII coated vesicle formation

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6
Q

How does packaging of large cargo occur

A

packaging proteins and procollagen

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BMS242 Cell & Molecular (14 decks)

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