vertigo drug

Question 1

list some examples of Antihistamines

Answer 1

-Meclizine
-Dimenhydrinate
-Diphenhydramine

Question 2

MOA of meclizine, antihistamines

Answer 2

-Histaminergic neurotransmission via
central H1 receptors involved in the link
between neural mismatch signal and the
emetic centre of brain. Antihistamines will
reduce the neural mismatch signals
underlying motion sickness and vertigo

Question 3

adverse effects of dimenhydrinate

Answer 3

-Drowsiness
-Sedation
(meclizine is less
sedating so may
be the better
option)

Question 4

patient requested for a non drowsy medication for antihistamines, which drug will you prescribe?

Answer 4

meclizine

Question 5

List an example of Anticholinergics

Answer 5

E.g.:
-Scopolamine

Question 6

MOA Of scopolamine

Answer 6

-Like the histaminergic pathways,
cholinergic neurotransmission is involved in
pathways underlying sensory inputs and
brain emetic centre. Blocking these
pathways may reduce the neural mismatch
signals underlying motion sickness and
vertigo

Question 7

side effects of anticholinergic

Answer 7

Drowsiness
-Sedation
-Dry mouth, dilated
pupils and other
anticholinergic
effects

Question 8

adverse effects of benzodiazepine

Answer 8

Ataxia, euphoria,
Incoordination,
somnolence,
hypotension,
headache,
dizziness, blurred
vision