Ventricles and CSF Flashcards

1
Q

What are the ventricles of the brain?

A

Lateral Ventricles (paired)
Third
Fourth
and then theres a central canal

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2
Q

What shape are the lateral ventricles?

A

C-shaped

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3
Q

Where does the third ventricle develop?

A

In the diencephalon which is the upper part of the brainstem

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4
Q

Where does the fourth ventricle develop?

A

In the metencephalon and myencephalon

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5
Q

Where is the central canal?

A

It is continuous down into the spinal cord, it runs from the 4th ventricle to the tip of the spinal cord

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6
Q

Where do the lateral ventricles develop?

A

They develop in the telencephalon which becomes the cerebrum

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7
Q

What are the components of the lateral ventricle?

A
Anterior horn
Body
Posterior horn
Atrium
Inferior Horn
Foramen of Monro ( which is also called the interventricular foramen)
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8
Q

What does the Foramen Monro or Interventricular Foramen provide communication between?

A

Between lateral ventricles and the third ventricle

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9
Q

What is the component of the third ventricle?

A

The aqueduct of Sylvius (Cerebral Aqueduct)

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10
Q

What does the Aqueduct of Sylvius (Cerebral Aqueduct) provide communication between?

A

The third and fourth ventricles

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11
Q

What are the important components of the fourth ventricle?

A

The Median Aperature (Foramen of Magendie) which is a single structure

and the Lateral Aperature (Foramina of Luschka) which is paired

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12
Q

What does the Lateral Aperature do?

A

Drains CSF into Pontine Cistern

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13
Q

What do the Median and Lateral Aperatures do, collectively?

A

They communicate with cisterns in the subarachnoid space which is important for the flow of CSF

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14
Q

What specific cistern will the Median Aperature or Foramen of Magendie communicate with?

A

Cisterna Magna

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15
Q

What specific cistern will the Lateral Aperature, or Foramina of Luschka communicate with?

A

Pontine cistern

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16
Q

What is the flow route of CSF?

A

Lateral ventricle –> third ventricle via the Foramen of Monro –> 4th ventricle via Aqueduct of Sylvius –> Pontine Cistern via Lateral Aperature OR the Cisterna Magna via Median Aperature

17
Q

Where is CSF produced?

A

Choriod Plexus via specialized epithelial cells

18
Q

What forms the ependyma?

A

The innermost layer of the neural tube

19
Q

What is the composition of CSF?

A

It is colorless, with a few cells, and has lower protein, glucose, and lipid than plasma

20
Q

Where is CSF produced?

A

In the lateral, 3rd, and 4th ventricles

21
Q

What is the function of CSF?

A

Filtration of blood, transport of ions (active) and transport of H2O (passive)

Important for transport and maintenance of homeostasis

22
Q

What is the total volume of CSF?

A

150 ml

23
Q

How many ml of CSF is produced per day?

A

500 ml/day

It turns over 3-4x a day

24
Q

What is the direction of flow of CSF and why?

A

CSF always flows from subarachnoid space => venous system because pressure in the venous system is lower

25
Q

How does the CSF drain?

A

You get rid of it via arachnoid villus –> Venous system in the superior sagittal sinus

26
Q

If the path takes you through the Median Aperature of the fourth ventricle, where will the CSF end up?

A

Subarachnoid space of the brain

27
Q

If the path takes you through the Lateral Aperature of the fourth ventricle, where will the CSF end up?

A

Subarachnoid space of the spinal cord

28
Q

What is the circulation pathway of CSF?

A

Lateral ventricles through the foramen of monro to the third ventricle, through the foramen of sylvius to the fourth ventricle, then from the fourth ventricle they will either go through the median aperature or the lateral aperature, which will take them either through the cisterna magna (median aperature) or the pontine cistern (lateral) to the subarachnoid space of either the cerebral hemispheres (median aperature) or the spinal cord (lateral aperature) to the dural sinus, and eventually to the venous system

29
Q

What are the functions of the CSF

A

Physical support and protection by acting as a cushion
Regulates chemical environment by eliminating waste
Chemical communication for the CNS to maintain homeostasis

30
Q

What is Hydrocephalus

A

Excess production of CSF
Blockage of ventricles/CSF due to tumors
Deficiency of CSF reabsorption due to the absence of arachnoid villi - this causes an overload to the ventricular system
Can also occur due to aqueductal stenosis which is narrowing of the aqueducts

31
Q

What is a choriod plexus patholoma?

A

Tumor of the choriod plexus, creating a miscommunication and causing overproduction of CSF

32
Q

What is a possible correction for Hydrocephalus?

A

A shunt to the ventricle that will drain the excess CSF into the abdomen

33
Q

What happens if you do not correct hydrocephalus?

A

permanent cognitive and functional brain damage