Ventilation and Perfusion Flashcards
ventilation
process by which air moves in and out of lung
perfusion
process by which deoxygenated blood passes through lungs and becomes oxygenated
what does the ventilation: perfusion ratio determine
Levels of O2 and CO2 in the blood
what effects does gravity (down and away from chest walls) have on the distribution of ventilation in the lungs
- pleural pressure is more negative at the apex than the base
- transpulmonary pressure is greater at base than apex
- increased alveolar volume in apex
compliance
refers to elasticity of the tissue, high compliance = lungs and chest wall expand easily
decreased compliance is common in pulmonary conditions
resistance
refers to any narrowing or obstruction of the airways.
high resistance is common in pulmonary conditions
what are the two types of dead space
- anatomical - volume of gas from each breath that fills the conducting airways
- physiological - total volume of gas in each breath not used in gas exchange e.g alveoli filled but not perfused
pulmonary circulation
brings deoxygenated blood from the heart to the lungs to be oxygented
bronchial circulation
brings oxygenated blood to lung tissues
what effect does gravity have on pulmonary circulation
greater blood flow to the base than the apex
anatomical shunt
sees deoxygenated blood bypass the pulmonary capillaries therefore bypassing gas exchange
physiological shunt
seen when there is an obstruction in the airways meaning alveoli not ventilating therefore blood passing is not perfused
COPD
airflow obstructed
includes emphysema and chronic bronchitis
pulmonary fibrosis
decreases elasticity and gas exchange