Vector mediated Apicomplexa Flashcards
Hepatozoon species use what for definitive host and what for vectors?
blood feeding insects for both
What cell type does Hepatozoon species infect?
Leukocytes
How do animals become infected with Hepatozoon?
Ingesting the intermediate host
What is the species that causes American canine hepatozoonosis?
Hepatozoon americanum
What transmits Hepatozoon americanum?
Gulf coast tick
When dogs are the _____ for Hepatozoon americanum, they can become sick
intermediate host
What is the life cycle of Hepatozoon americanum in the tick?
Takes up gamonts via leukocyte ingestion
Sporulated oocysts develop in the tick
Describe the life cycle of Hepatozoon americanum in the dog
Infected via ingestion of the tick containing oocysts
Sporozoite infects macrophage; may reside in onion skin cysts
Merogony takes place in the cyst between muscle layers
Gametogony happens in monocytes
What are the clinical signs in a dog infected with Hepatozoon americanum?
Fever that is intermittent due to merozoite release –> local inflammation and systemic reaction
Myalgia, myasthenia, and are reluctant to move
How would you diagnose Hepatozoon americanum?
Muscle biopsy looking for cysts
T/F The best treatment for this is metronidazole
FALSE; this is something they will likely just have to learn to live with
What are the three important Piroplasms we need to know?
Babesia spp.
Theileria spp.
Cyatauxzoon spp.
What is a unique feature of Piroplasms?
Only asexual phase is seen in vertebrates
Sporozoites are injected with the tick bite
What is the definitive host of Babesia? How is it transmitted?What are the IH we are concerned with?
Ioxid tick
Tick bite
Dogs, cattle, and horses
What is the life cycle of Babesia?
Gametogony occurs within tick, innoculates host with sporozoites with bite.
Directly infects RBCs of host
Develop into prioplasms and replicate into merozoites
merozoites become gamonts, which are then ingested by the tick when feeding, and lifecycle restarts