Vasvular Flashcards

1
Q

Three characteristics of stable angina

A

squeazing, crushing sensation in chest

1) precipitated by stress or exercise
2) relieved by rest or nitrates
3) recover lasts less than 15 min

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2
Q

ECG findings in pericarditis

A

Saddle shaped ST elevation

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3
Q

Systolic ejection murmur

A

Pulmonary stenosis

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4
Q

Type A vs type B aortic dissection

A

Type A: ascending aorta or arch

Type B: the rest

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5
Q

Treatment for haemodynamically unstable AF.

A

Synchronised cardioversion

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6
Q

How does GTN spray work

A

Forms free NO which increases cGMP in smooth muscle and toner tissues, leading to decreased intracellular calcium and vasodilation

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7
Q

Hypertension levels

A

140/90 or 135/85

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8
Q

Mid systolic click, late systolic murmur

A

Mitral prolapse

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10
Q

Medical management of MI pre PCI

A
MONA
Metoclopramide
Opiates/oxygen 
GTN
Aspirin 
Plus antiplatelet
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11
Q

5H and 4T of pulseless cardiac arrest

A

Hypovolaemia, hypoxia, hydrogen ions (acidosis), hyper/hypokalaemia, hypothermia
Toxins (tricyclics, cocaine), tamponade, tension pneumo, thrombosis

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12
Q

First line medication for 2nd degree block

A

Atropine

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13
Q

Diastolic murmur, pounding heart when lying on left side. Best heard at right parasternal edge

A

Aortic regurgitation

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14
Q

Gold standard investigation for unstable angina

A

Coronary angiography (if GRACE risk >3%) with PCI if indicated

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15
Q

Risks in AF

A

Stroke, HF. Consider anticoagulation using CHADS.

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16
Q

Medical management of heart failure and effects of medications

A

Loop diuretics: increase sodium and water excretion in the ascending loop of henle.
ACE inhibitors usually started first, then add a beta blocker.
If intolerant to ACE, can give Angiotensin II blockers instead.
Add an aldosterone antagonist (e.g. spironolactone if needed).

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17
Q

Indications for PCI in MI

A

Presentation within 12h and PCI can be delivered within 120min of time when fibrinolysis could have been given,

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18
Q

Diastolic murmur, loud P2, pink cheeks

A

Mitral stenosis

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19
Q

Management of aortic dissection

A

Type A usually always need surgical repair.

Type B can be conservative management, with fastidious blood pressure control (b blockade, sodium nitroprusside).

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21
Q

Investigations in stable angina

A

If 1 characteristics, do ecg and check if abnormal. If it is or 2 + characteristics, do ecg and CTPA.

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22
Q
Arteries blocked in:
Buttock and hip
Thigh
Upper 2/3 calf 
Lower 1/3 calf 
Foot
A
Buttock and hip: iliac / aorta
Thigh: common femoral
Upper 2/3 calf: superficial femoral 
Lower 1/3 calf: popliteal
Foot: tibial/ peroneal
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22
Q

When to reverse anticoagulation in warfarin asymptomatic patient

A

INR > 8

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23
Q

Mid-late systolic murmur, crescendo decrescendo pattern, slow rising pulse, carotid radiation

A

Aortic stenosis

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24
Q

What investigations to perform in atrial fibrillation

A

ECG, cardiac enzymes (exclude MI), Sats to check for shock. If patient is going to have cardio version (synchronised on R wave), a transesophageal echo is required to check for any thrombus which may be dislodged during procedure

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25
Q

Second degree type I and II block and II:I block

A

Type I: lengthening PR
Type II sudden non progressive lengthening of PR interval and block of QRS complex.
2:1 block is 2 p wave for each QRS

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27
management of patients with QRISK >10%
Offer: atorvastatin 20mg. If existing CV disease, atorvastatin 80mg.
28
When is surgical valve replacement/ repair indicated
LVEF <50%, end diastolic volume >75 or end systolic volume >55
28
First line investigation in AAA suspicion
Abdo US
29
What medication should be avoided with b blockers
Verapamil
30
Post MI medications
``` B blocker Ace inhibitor/ ang II High dose statin PPI Aspirin (life) + second clopidigrel (min 12 months) ```
31
Common cause of endocarditis in IV drug users
Coagulase negative streptococci
31
Antihypertensive managements
55+ or black: Ca channel blocker (e.g. ramipril) 55- and white or renal impairment: start ACE inhibitor (e.g. verapamil) Second line add the other one. Consider ACE + thiazides diuretic. B blocker if concomitant heart failure
32
Absence of P wave with irregularly irregular ventricular rhythm and chaotic atrial rhythm
Atrial fibrillation
33
Pan systolic murmur at the apex radiating to the axilla, AF.
Mitral regurgitation
34
CHADVASC score
Used for stroke risk in patients with AF C congestive heart failure H hypertension A2 age (65+ 1, 75+ 2) D diabetes S2 previous stroke/ thromboembolic disease VA: vascular Hx, prior MI, peripheral artery disease, aortic plaques. S: sex (females get a point) Anticoagulation if 1+ in males and 2+ in females
35
What artery supplies the anteroseptal heart
Left anterior descending
36
What artery supplies the lateral heart
Left circumflex
37
What artery supplies the inferior aspect of the heart
Right coronary artery
38
What artery supplies the anterolateral aspect of the heart
Left anterior descending or left circumflex
39
What artery supplies posterior aspect of the heart
Left circumflex/ right coronary
40
CHADVASC score
Used for stroke risk in patients with AF C congestive heart failure H hypertension A2 age (65+ 1, 75+ 2) D diabetes S2 previous stroke/ thromboembolic disease VA: vascular Hx, prior MI, peripheral artery disease, aortic plaques. S: sex (females get a point)
41
What artery supplies the anteroseptal heart
Left anterior descending
42
What artery supplies the lateral heart
Left circumflex
43
What artery supplies the inferior aspect of the heart
Right coronary artery
44
What artery supplies the anterolateral aspect of the heart
Left anterior descending or left circumflex
45
What artery supplies posterior aspect of the heart
Left circumflex/ right coronary
46
Molecule which is highly expressed in atherosclerosis
Vascular cell adhesion molecule (VCAM-1)
47
Causes of pericarditis
Common in patients with transmural MI, neoplasms, male sex. Dressler’s syndrome is common 2-6 weeks following an MI, autoimmune mediated
48
Signs and symptoms of pericarditis
Retrosternal chest pain worst on lying down and inspiration, pericardial friction rub can be heard, fever.
49
Explain ventricular free wall rupture
Occurs 1-2 weeks after MI. Patients present with acute heart failure due to cardiac tamponade (raised JVP, pulses paradoxus, diminished heart sounds). Urgent pericardiocentesis and thoracotomy
50
Explain ventricular septal defect in MI
Rupture of the interventricular septum, occurs 1-2 weeks after an MI. Patient will present with acute heart failure with a pan systolic murmur. Surgery and echo are warranted.
51
Common complication of infero- posterior infarction
Acute mitral regurgitation - due to ischaemia and rupture of papillary muscles.
52
Molecule which is highly expressed in atherosclerosis
Vascular cell adhesion molecule (VCAM-1)
53
Causes of pericarditis
Common in patients with transmural MI, neoplasms, male sex. Dressler’s syndrome is common 2-6 weeks following an MI, autoimmune mediated
54
Signs and symptoms of pericarditis
Retrosternal chest pain worst on lying down and inspiration, pericardial friction rub can be heard, fever.
55
Explain ventricular free wall rupture
Occurs 1-2 weeks after MI. Patients present with acute heart failure due to cardiac tamponade (raised JVP, pulses paradoxus, diminished heart sounds). Urgent pericardiocentesis and thoracotomy
56
Explain ventricular septal defect in MI
Rupture of the interventricular septum, occurs 1-2 weeks after an MI. Patient will present with acute heart failure with a pan systolic murmur. Surgery and echo are warranted.
57
Common complication of infero- posterior infarction
Acute mitral regurgitation - due to ischaemia and rupture of papillary muscles.
58
Troponin complex binding site
Troponin C: binds to calcium to activate muscle contraction (cardiac and skeletal) Troponin T: binds tropomyosin to form complex Troponin I: binds to actin to hold the complex in place. T and I are specific markers of myocardial necrosis
59
Wolff Parkinson white syndrome ECG
Short PR, delta wave (slurred upstroke QRS). Axis deviation on opposite side of accessory pathway
60
Explain BNP and significance of levels
BNP gets released in heart failure due to increased filling pressure. It has diuretics natriuretic and antihypertensive. BNP: <35 NT pro-BNP: <125
61
When would you recommend cardiac desynchronisation therapy defibrillator?
In HF with LVEF <35 despite treatment and sinus rhythm LBBB QRS duration >130ms
62
What is Af
AF is chaotic electrical excitation within the atrium, with sites producing depolarization that sometimes conduct to the ventricle leading to irregularly irregular pulse
63
Common area for clot formation in af
Atrial appendage
64
Organism causing rheumatic fever
Streptococcus pyogenes (group A streptococcus gram +)
65
3 electrolyte causes of long QT
Hypokalaemia, hypocalcaemia, hypomagnesemia