Rheumatology Flashcards
Medical management Of gout vs pseudogout
Change thiazides to losartan, give NSAIDs for acute flairs. Allopurinol after it settles. Pseudogout usually resolves spontaneously but can give NSAIDs.
Investigation results in SLE
Positive ANA and anti-smith specific.
Systemic sclerosis antibodies
Anti-centromere (limited cutaneous sclerosis) anti SCL70 (diffuse systemic sclerosis).
Nail fold calilaroscopy usage
Systemic sclerosis
Association of temporal or giant cell arthritis
Polymyalgia rheumatica (pain and stiffness in shoulders pelvis and neck)
Main gene in Ankylosing spondylitis
HLA B27
Progressive muscle and pain and weakness, proximally and bilaterally. Diagnosis and investigation k
Polymyositis, muscle biopsy and positive anti-jo1
Plaques on elbows and knee, purple rash on face and eyelids, peri orbital oedema amd muscle weakness. Diagnosis and investigation
Dermatomyositis. Anti-mi2, ANA, CK>1000. Loot for associated cancers
Failure to thrive, voracious appetite, wet sounding cough absence of vas deferens investigation and diagnosis
Cystic fibrosis (CFTR gene), sweat test.
Sjögren’s syndrome main test
Sherman’s test.
Which hernia can be pushed back
Direct ones