Vasopressin

Question 1

Vasopressin Class

Answer 1

Pituitary (antidiuretic) hormone

Question 2

Vasopressin MOA

Answer 2

Causes vasoconstriction (pressor effect) of peripheral, cerebral, pulmonary, and coronary vessels

Question 3

Vasopressin Indications and Field Use

Answer 3

Adult shock-refractory Vfib/pulseless Vtach

Question 4

Vasopressin Contraindications

Answer 4

• Responsive patient with coronary artery disease

* Hypertension

Question 5

Vasopressin Adverse Reactions

Answer 5

• Can increase peripheral vascular resistance and provoke cardiac ischemia and angina pectoris
• Abdominal distress
• Nausea and vomiting
• Tremors
• Tissue necrosis if extravasation occurs

Question 6

Vasopressin Incompatibilities

Answer 6

None in emergency setting

Question 7

Vasopressin Adult Dosage

Answer 7

For ventricular fibrillation/pulseless ventricular tachycardia: 40 U one time-may replace the FIRST or SECOND dose of epinephrine.

Question 8

Vasopressin Pediatric Dosage

Answer 8

N/A

Question 9

Vasopressin Routes

Answer 9

IV, IO, ET

Question 10

Vasopressin Onset

Answer 10

1-3 minutes

Question 11

Vasopressin Peak Effects

Answer 11

5-10 minutes

Question 12

Vasopressin Duration

Answer 12

10-35 minutes

Question 13

Vasopressin Drug Box Minimum

Answer 13

Optional 40 units