Furosemide Flashcards
Furosemide Class
Loop diuretic
Furosemide MOA
Inhibits electrolyte reabsorption in the ascending Loop of Henle. Promotes excretion of sodium, potassium, chloride. Vasodilation increases venous capacitance and decreases afterload.
Furosemide Indications
Pulmonary edema, CHF
Furosemide Contraindications
- Anuria (relative)
- Hypovolemia
- Hypotension
Furosemide Adverse Reactions
- May exacerbate hypovolemia
- Hyperglycemia (due to hemoconcentration)
- Hypokalemia
- May decrease the response to pressors
Furosemide Incompatibilities and Drug Interactions
Increased effects with other antihypertensives
Furosemide Adult Dosage
On oral furosemide therapy: Consider initial dose of 2 times daily oral dose, if no effect in 20 minutes may double initial dose.
Not on oral furosemide therapy: 0.5-1 mg/kg to a maximum of 2 mg/kg (usually 20-40 mg) IV slowly.
Furosemide Pediatric Dosage
1 mg/kg IV slowly
Furosemide Routes
Slow IV push
Furosemide Onset
5 minutes (vasodilation)
Furosemide Peak Effects
20-60 minutes (diuresis)
Furosemide Duration
Variable
Furosemide AZ Drug Box Minimum
Optional 100 mg