Vasopressin

Question 1

Vasopressin Class:

Answer 1

Non- adrenergic peripheral vasoconstrictor

Anti-diuretic hormone (ADH)

Question 2

Vasopressin Mechanism of Action:

Answer 2

Stimulation of V1 smooth muscle receptors, potent vasoconstrictor when given in high doses.

Question 3

Vasopressin Indications:

Answer 3

-Adjunct in the treatment of diabetes
-Unlabeled and investigational
-Cardiac arrest situations caused by Ventricular fibrillation,
pulseless ventricular tachycardia, pulseless electrical activity (PEA)
-Alternate vasopressor to the first or second dose of epinephrine in cardiac arrest, may be useful in cases of vasodilatory shock.

Question 4

Vasopressin Adult Dose:

Answer 4

40 units (as a single dose only) IV or IO to replace the first or second dose of epinephrine in cardiac arrest

Question 5

Vasopressin Pediatric Dose:

Answer 5

Not used