Magnesium Sulfate Flashcards

1
Q

Magnesium Sulfate: Class

A

Electrolyte

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2
Q

Magnesium Sulfate: Mechanism of Action

A
  • Reduces striated muscle contractions and blocks peripheral neuromuscular transmission by reducing acetylcholinesterase release at the myoneural junction
  • Manages seizures in toxemia of pregnancy
  • Induces uterine relaxation
  • Can cause bronchodilation after beta-agonists and anticholinergics have been used
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3
Q

Magnesium Sulfate: Indications

A
  • Seizures of eclampsia (Toxemia of pregnancy)
  • Torsades de Pointes
  • Hypomagnesemia
  • TCA overdose-induced dysrhythmias
  • Digitalis-induced dysrhythmias
  • Class IIa agent for refractory VF and VT after administration of Lidocaine doses
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4
Q

Magnesium Sulfate: Adult Dose

A
  • Seizure activity associated with pregnancy: 1-4 gm IV over 10 minutes.
  • Torsades de Pointes or Refractory VF/VT: 1-2 gm IV over 1-2 minutes.
  • Asthma: 1-2gm IV.
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5
Q

Magnesium Sulfate: Pediatric Dose

A
  • Asthma/bronchospasm, severe: 25 mg/kg over 10 minutes IV.

- Usually mixed in 50-100 CC of NS to be given IV.

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