Vasculitis Types

Question 1

Wegener’s granulomatosis

Answer 1

pulmonary and renal

Question 2

Polyarteritis nodosa

Answer 2

Hepatitis B ( high incidence)

Question 3

Takayasu’s arteritis

Answer 3

large vessel condition attack aorta

Question 4

Henoch-Schönlein purpura

Answer 4

pappüble purpura on butt and LE and kidney and lung involvement - abdominal pain in kids

Question 5

Cryoglobulinemic vasculitis

Answer 5

Hepatitis C, cold precipitate (temps)

Question 6

Churg-Strauss syndrome

Answer 6

vasculitis of the lungs ( asthma and hempptysis) also seen in pulmonary eosinophilia

Question 7

Kawasaki disease

Answer 7

mucocutaneous lymph node syndrome ( aneurysms on cornea?

Question 8

Behçet’s syndrome

Answer 8

ulcers on mouth and genitals

Question 9

Microscopic polyangiitis
Idiopathic cutaneous vasculitis
Isolated vasculitis of the central nervous system
Cogan’s syndrome

Answer 9

last few

Question 10

Pathogenic immune complex formations ?

Answer 10

Henoch-Schönlein purpura

maybe a sudden URI, and you created all these immune complexes and they get stuck in very small vessels ( capillaries) - lungs and kidneys ( small vessel disease) - kidney damage and lung damage - usually on LE and butt. The ABS attack whatever condition it thinks is not self.

Question 11

Production of antineutrophilic cytoplasmic bodies?

Answer 11

Wegener’s granulomatosis

likes small vessels ( lung and kidneys) - damage

Question 12

Pathogenic T lymphocyte responses and granuloma formation ?

Answer 12

Giant cell arteritis

T cells attack self - large vessel condition

Question 13

Large vessel vasculitis ?

Answer 13

PTT

Polymyalgia rheumatica ( stiffness in shoulder and joints),

Takayasu’s arteritis aorta

Temporal arteritis

Question 14

Medium vessel vasculitis?

Answer 14

KP

Kawasaki disease - potential coronary artery aneurysm

Polyarteritis nodosa - Hep B

Question 15

Small vessel ( hits more categories)

Answer 15

Wegener’s granulomatosis

Henoch-Schönlein purpura buttocks and lower extremities

Cryoglobulinemic vasculitis

Churg-Strauss syndrome - lungs

Behçet’s syndrome oral and genital ulcers ( mucocutaneous areas)

Question 16

Vasculitis Treatment

Answer 16

Corticosteroids
Cytotoxic agents
      Cyclophosphamide
      Methotrexate
Immunoglobulins

Question 17

Vasculitis Gold standard diagnostic study

Answer 17

Biopsy

Question 18

syphilis DDX or comorbid signs?

Answer 18

vasculitis like presentation around thoracic aorta