The Stomach Mucosa and the Gastric Glands Flashcards
Exocrine cells?
Mucous cells
Chief cells
Parietal cells
Endocrine/ Paracrine cells?
ECL cells ( enterochromaffin like)
G cells
D cells
Mucous cells product secreted?
Alkaline mucus
Chief cells product secreted?
Pepsinogen
Parietal cell product secreted?
HCl
IF
ECL cells product secreted?
Histamine
G cells product secreted?
Gastrin
D cells product secreted?
Somatostatin
Mucous cells stimuli for secretion?
mechanical stimulation by contents
Chief cells stimuli for secretion?
Each, gastrin
Parietal cells stimuli for secretion?
ACh, gastrin, histamine
ECL cells stimuli for secretion?
Each, gastrin
G cells stimuli for secretion?
Protein products, ACh
D cells stimuli for secretion?
Acid
Mucous cell function of secretory product?
Protects mucosa against mechanical, pepsin, and acid injury
Chief cell function of secretory product?
When activated, begins protein digestion
Parietal cell function of secretory product: HCl??
Activated pepsinogen,
breaks down connective tissue
denatures proteins
kills microorganisms
Parietal cell function of secretory product: IF??
facilitates absorption of Via. B12
ECL cells function of secretory product?
stimulates parietal cells
G cells function of secretory product??
stimulates parietal, chief, and ECL cells
D cell function of secretory product?
inhibits parietal, G, and ECL cells
somatostatin - stops everything
Octreotide