Vasculitis

Question 1

What are the common symptoms of SLE?

Answer 1

Arthritis (48%)
Malar rash (31%)
Nephropathy 27
Photosensitivity 
Neurologic involvement
Fever.
Raynauds
Serositis
Thrombocytopenia
Oral ulcers

Question 2

What main FBC show in SLE?

Answer 2

Low RBC
Low lymphocytes
Low platelets

Question 3

Examples of large vessel vasculitis?

Answer 3

Takayasu arteritis

Giant cell arteritis

Question 4

Examples of medium vessel vasculitis

Answer 4

Kawasaki disease

Polyarteritis nodosa

Question 5

Examples of immune complex small vessel vasculitis

Answer 5

Cryoglobulinemia vasculitis
IgA vasculitis (henoch-schonlien)
Hypocomplementric urticarial vasculitis (anti-c1q)
Anti-GBM disease

Question 6

Examples of ANCA associated small vessel vasculitis

Answer 6

Microscopic polyangiitis
Granulomatosis with polyangiitis (wegners)
Eosinophilic granulomatosis with polyangiitis (c-S)

Question 7

Presentation of takayasu?

Answer 7

Inflammatory phase then pulseless phase

Unequal blood pressures
Absent pulses 
Claudication 
Renal artery stenosis 
Fainting (subclavian steal syndrome and carotid sinus hypersensitivity)

Question 8

What is the cause of vision disturbance in GCA?

Answer 8

Anterior ischemic optic neuropathy

Question 9

What’s seen on temporal artery biopsy in GCA?

Answer 9

Skip lesions

Question 10

What is buergers disease?

Answer 10

Medium vessel vasculitis - of lower limb

Present in young male smokers
Angiography - tortuous corkscrew vessels

Question 11

Treatment for acute GCA?

Answer 11

High dose steroids 60mg for 5-7days, guided by symptoms and ESR.