vasculitides Flashcards
define vasculitis ?
inflammation and necrosis of blood vessels
how can we catagorise vasculitis?
• LARGE • Giant cell arteritis • Takayasu's arteritis • MEDIUM • Polyarteritis nodosa • Kawasaki's disease • SMALL - ANCA associated vasculitis - Immune complex small vessel vasculitis
specific signs of GCA?
loss of vision, jaw claudication, headache, scalp tenderness
specific signs of Polyarteritis Nodosa?
microaneurysms, thrombosis, infarctions, hypertension, testicular pain
specific signs of Henoch-Schonlein Purpura
purpura, arthritis, gut symptoms, glomerulonephritis, IgA deposition
specific signs of Wegner’s Granulomatosis?
nasal bleeding and deformity, haemoptysis, sinusitis, glomerulonephritis, saddle nose
specific signs of Churg Strauss?
asthma, eosinophilia, associated with UC, primary sclerosing cholangitis
which autoantibodies are seen in wegners?
o cANCA
which autoantibodies are seen in goodpastures?
o anti-GBM
which autoantibodies are seen in Churg-Strauss
o pANCA
what might be seen in the urine?
haematuria, proteinuria
seen in glomerulonephritis in wegners
