Polymyositis and dermatomyositis Flashcards
1
Q
what is Polymyositis ?
A
inflammatory disorder causing symmetrical, proximal muscle weakness
2
Q
what is dermatomyositis?
A
this is a variant of the disease where skin manifestations are prominent.
3
Q
epidemiology of these conditions?
A
Typically affects middle aged women
4
Q
what are the presenting symptoms of polymyositis ?
A
o Diffuse weakness in proximal muscles o Raynaud’s o Respiratory muscle weakness o Interstitial lung disease o Dysphagia o Dysphonia
5
Q
what are the features of Dermatomyositis?
A
o Features of polymyositis
o Photosensitivity
o Macular rash over the back and the shoulder
o Heliotrope rash in the periorbital region
o Gottron’s papules
o Mechanics hands
6
Q
gold standard investigation for these conditions?
A
o Muscle biopsy
7
Q
what might the bloods show?
A
high Creatine kinase
8
Q
which antibody is associated with Dermatomyositis?
A
ANA
9
Q
what other investigation might be useful?
A
EMG
