Vasculature Flashcards
Dura
Thick/tough collagenous membrane that adheres to surface of skull and second meningeal layer, arachnoid
Arachnoid
Thin membrane of cells interspersed w/ bundles of collagen; arteries extend and CSF flows in the space between arachnoid and pia – this is subarachnoid space. CSF enters venous circulation via arachnoic villi/granulations
Pia
Delicate membrane that hugs surface of CNS and consists of single cell layer plus astrocyte processes.
BBB main transport
facilitated trxport assist mvmt of glucose and large neutral AA’s down concentration gradient. Active tport move molecules across BBB. channels regulate ions. Enzyme systems w/in the endothelial cells convert transported molecules into metabolites that are transported across BBB
Flow of CSF
1) Produced in choroid plexus in LV, 3V and 4V.
2) Ventricles are interconnected; LV and 3V by FMo, and 3V and 4V by CA, aka Sylvius
3) CSF exits to subarachnoid space via foramina in IVth ventricle.
4) CSF accumulates in cisterns (SC, Cisterna Magna, interpeduncular cistern, pontine, lumbar).
5) CSF flows into superior sagittal sinus via AG’s.
Arteries supplying spinal cord
1) Ant. and Post spinal arteries (branches of vertebral arteries)
2) Radicular arteries (branches of segmental arteries that branch off aorta)
Anterior Cerebral artery (territory)
Medial frontal and parietal lobes
Middle cerebral artery (territory)
lateral frontal and parietal lobes; lateral/medial/superior temporal
PCA territory
inferior temporal and parietal; lateral/medial/inferior occipital
Thalamus supply
PCA
Caudate supply
ACA
Putamen supply
MCA
Globus pallidus supply
Anterior choroidal, MCA
Brain stem supply
vertebro-basilar system
PICA territory
dorsolateral medulla (and cerebellum) --> Wallenberg syndrome w/ PICA occlusion
Ventral and central pons
Basilar artery