Vascular Function and its Control Flashcards
What determines MAP?
TPR and CO
What determines MAP?
TPR and CO
At rest where is most of the blood in the circulation?
In the veins
Which vessels have more compliance?
Veins
Which vessels are more sensitive to a change in volume?
Arteries
What happens to venous pressure when there is an increase in cardiac output?
Venous pressure drops - this is because it will increase blood to the arteries but TPR stays the same so the blood does not flow through the the veins
What happens to cardiac output when there in an increase in venous pressure?
Cardiac output increases
What is the pressure in the SVC and IVC?
1 to 5 mmHg - slightly higher than right atrial pressure
How is venous pressure and atrial pressure assessed?
JVP
What happens to venous pressure with an decrease in TPR?
Venous pressure increases
What is central venous pressure?
The filling pressure for the heart
When does central venous pressure rise?
Due to a failing heart
When does central venous pressure fall?
When venous return is poor
What is the role of the endothelium?
produces substances that alter smooth muscle contraction and mediates the action of circulating substances
What substances alter smooth muscle contraction?
NO (dilate), endothelin (constrict), prostaglandin (both)
