Vascular Ds In Kidney Flashcards
Large vessel kidney disease
Renal artery stenosis
Renovascular HTN
Small vessel kidney disease
Thrombotic microangiopathy
Most common cause of renovascular htn
Atherosclerosis
Mc xause of renovascular htn in young
Fibromuscular dysplasia
Mcc of renovascular htn in india
Takayasu arteritis F>M
String of bead appearance on ct renal angiogram is seen in
Fibromuscular dysplasia
Non inflammatory arteriopathy
Tunica media fibroplasia i e fibromuscular dysplasia
Fibromuscular dysplasia involves with part of renal artery
Mid and distal renal artery
Treatment of fibromuscular dysplasia
PTRA
Percutaneous transluminal renal angioplasty
Vascular kidney ds progressing to ckd k/a
Ischemic nephropathy
BP =CO ×PR
Sustained rise of BP can be due to
Why increase cardiac output cannot cause sustained bp rise
Increase PR
Pressre natriuresis
Unilateral ras symptom will be -
Urine output will be
Usg finding-
Htn
Normal urine output
Asymmetrical kidney upto 1 cm
Flash pulmonary edema and low urine outputin b/l ras is due to
Treatment?
Due to increase volume overload as both kidney are not able to excrete sodium
Diuretics
If kidney size is more than 8cm with u/l and B/l ras
Treatment
U/l ptra + stenting
B/l statin +Antiplatelet +smoking cessation
Triad seen in thrombotic microangiopathy
MAHA
Thrombocytopenia
Microcirculatory occlusion by platelet thrombi
Thrombotic microangiopathy in kidney is aka
In brain is aka
Kidney HUS
brain TTP
HeLLP syndrome
Hemolysis
Elevated liver enzymes
Low platelet count
Childhood HUS occurs to due
90% D+HUS EHEC - shiga like toxin Shigella dysentriae -shiga toxin type 1 10% Neuraminidase producing strep pneumonia
Childhood cause of B/L RVT
ADULT CAUSE
ELDERLY
A dehydration
B membranous nephropathy
C rcc
Most common genetic cause of atypical HUS
Alternate complement pathway activation
Complement factor H mutation
Sporadic cause of atypical hus
Drugs mitomycin tacrolismus clopidogrel Hiv Preg Sle Post transplant recurrence
Only treatment in adult hus to salvage kidney
Plasma exchange within 24 hrs