Vascular Disorder

Question 1

Tendency to bruise easily or bleed spontaneously yields normal platelet and blood coagulation

Answer 1

Vascular disorder

Question 2

3 Hereditary vascular disorders

Answer 2

Hereditary hemorrhagic telangiectasia
Hemangioma thrombocytopenia syndrome
Ehlers Danlos syndrome

Question 3

Organisms that causes HUS (Hemolytic Uremic Syndrome)

Answer 3

Shigella dysenteriae
E coli 0157:H7

Question 4

Hereditary hemorrhagic telangiectasia also known as

Answer 4

Osler-Weber-Rendu disease

Question 5

Cardinal signs of HUS (Hemolytic Uremic Syndrome)

Answer 5

Hemolytic anemia
Renal failure
Thrombocytopenia

Question 6

Autosomal dominant resulting in dilated superficial blood vessels, thin walled blood vessel with discontinuous endothelium and inadequate or missing elastin and most common inherited vascular disorder

Answer 6

Hereditary hemorrhagic telangiectasia

Question 7

Activation of coagulation cascade resulting to consumptive coagulopathy that entraps platelets in the intravascular fibrin clots

Answer 7

Disseminated Intravascular Coagulation (DIC)

Question 8

3 Other disorder with telangiectasia

Answer 8

Cherry red hemangiomas
Ataxia telangiectasia
Chronic actinic telangiectasia

Question 9

Type of DIC which is D dimer positive

Answer 9

Acute DIC (Disseminated Intravascular Coagulation)

Question 10

Telangiectasia in older men and women

Answer 10

Cherry red hemangiomas

Question 11

Type of DIC may not be detachable or slightly increased, usually causes by another underlying condition

Answer 11

Chronic DIC (Disseminated Intravascular Coagulation)

Question 12

Telangiectasia associated with louis bar syndrome

Answer 12

Ataxia telangiectasia

Question 13

3 Big spleen syndromes

Answer 13

Gaucher
Hodgkin
Sarcoidosis

Question 14

Hemangioma thrombocytopenia syndrome also known as

Answer 14

Kasabach-meritt syndrome

Question 15

secondary thrombocytosis
below 800,000 plts
moderate increase and asymptomatic

Answer 15

Reactive thrombocytosis

Question 16

associated with giant cavernous hemangioma, tumor, thrombocytopenia, bleeding diathesis
other features: acute and chronic DIC and microangiopathic hemolytic anemia

Answer 16

Hemangioma-Thrombocytopenia syndrome

Question 17

Primary thrombocytosis
elevated platelets (more than millions)
markedly increase

Answer 17

Autonomous thrombocytosis

Question 18

Treatment for HTS (Hemangioma thrombocytopenia syndrome)

Answer 18

corticosteroid therapy and surgery

Question 19

6 Acquired vascular disorders

Answer 19

1. Allergic purpura
2. Senile purpura
3. Paraproteinemia and amyloidosis
4. Drug induced vascular purpura
5. Vitamin C deficiency
6. Henoch-Schonlein purpura

Question 20

2 Qualitative disorders of platelets

Answer 20

Bernard-Soulier syndrome
Glanzmann thrombasthenia

Question 21

Group of nonthrombocytopenic purpura characterized by apparently allergic manifestations. It is associated with certain foods, drugs, cold, insect bites

Answer 21

Allergic purpura

Question 22

giant platelet syndrome, lack gp Ib/Ix/V, autosomal recessive

Answer 22

Bernard-Soulier syndrome

Question 23

autoimmune vascular injury, immunologic damage to EC, affecting boys ages 3-7 years of age after respiratory infection, palpable purpura, elevated: WBC and ESR

Answer 23

Henoch-Schonlein Purpura

Question 24

Drugs that causes drug induced vascular purpura

Answer 24

Aspirin
Warfarin
Barbiturates
Diuretics
Digoxin
Methyldopa
Sulfonamides
Iodides

Question 25

decreased synthesis of collagen, weakening of capillary walls and appearance of purpuric lesions

Answer 25

Vitamin C insufficiency causing purpura

Question 26

bruise, irregular in shape

Answer 26

Ecchymosis