Vascular Dementia (20%) Flashcards
1
Q
Pathophysiology
A
Reduced blood flow to the brain, secondary to small or large vessel disease
E.g. cerebrovascular damage e.g. stroke, TIA
2
Q
Clinical features
A
Step wise decline in cognitive function
Evidence of previous stroke
Depression and delusions
Emotional lability
Memory impairment
Gait disturbance and incontinence are sometimes seen
3
Q
Treatment
A
Optimise cardiovascular risk factors: to reduce the likelihood of further ischaemic events
Antihypertensives e.g. RAMIPRIL
AChE inhibitor or memantine: if there is suspected comorbid Alzheimer’s disease, Dementia with Lewy-Bodies or Parkinson’s disease
4
Q
Risk factors
A
Smoking
Diabetes
AF
Dyslipidaemia
Hypertension
Age