valvular heart disease pathology Flashcards

1
Q

aortic valve is in close proximity to the

A

AV node and bundle of HIs

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2
Q

subaortic curtain is continuous with

A

anterior leaflet of mitral valve

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3
Q

jet lesions are associated with

A

valvular heart disease

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4
Q

congenital aortic stenosis is often

A

bicuspid

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5
Q

congenital AS is associated with what type of ventricular hypertrophy

A
concentric 
and 
SAD
syncope
angina
dyspnea
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6
Q

marked fibrosis and focal calcification of valve cusps associated with

A

Chronic rheumatic valvulitis

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7
Q

2 features of a bicuspid aortic valve

A
  • raphe

- conjoined cusp - absent commisure

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8
Q

individuals with bicuspid valves also have other pathologies such as

A

Ascending aortic aneurysms

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9
Q

aortic stenosis can lead to what type of heart failure

A

Diastolic dysfunction with preserved ejection fraction

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10
Q

aortic insufficiency can be the result of

A

ascending aortic aneurysm

myocardial hypertrophy

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11
Q

Syphilitic/Luetic aortitis can lead to

A

aortic insufficiency

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12
Q

most common cause of rheumatic valvulitis is

A

mitral stenosis

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13
Q

what process is dominant in mitral stenosis

A

Fibrosis NOT calcification

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14
Q

“fish mouth” deformity of which valve is classic

A

mitral valve stenosis

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15
Q

Aschoff nodules are present where?

A

in mitral valve acute rheumatic valvulitis

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16
Q

most common cause of mitral regurgitation is

A

myxomatous mitral valve disease - associated with prolapse

17
Q

in mitral regurg there is increased ground substance deposition where?

A

middle layer of the leaflets - spongiosa

associates with marfan

18
Q

acute Mitral regurg can be the result of

A

papillary muscle rupture

19
Q

ischemic Mitral regurg is worse with what type of MI

A
  • Inferior wall MI of the left ventricle
20
Q

emboli from valve endocarditis can result in

A

Lung thrombi
infarcted bowel
stroke
gangrene

21
Q

3 things that can cause non-bacterial thrombotic endocarditis

A
  • mucin secreting cancers
  • hypercoagulable state
  • Collagen vascular disease
22
Q

2 complications of prosthetic valvles

A
  • thrombosis

- pannus overgrowth - fibrosis