valvular heart disease pathology Flashcards
aortic valve is in close proximity to the
AV node and bundle of HIs
subaortic curtain is continuous with
anterior leaflet of mitral valve
jet lesions are associated with
valvular heart disease
congenital aortic stenosis is often
bicuspid
congenital AS is associated with what type of ventricular hypertrophy
concentric and SAD syncope angina dyspnea
marked fibrosis and focal calcification of valve cusps associated with
Chronic rheumatic valvulitis
2 features of a bicuspid aortic valve
- raphe
- conjoined cusp - absent commisure
individuals with bicuspid valves also have other pathologies such as
Ascending aortic aneurysms
aortic stenosis can lead to what type of heart failure
Diastolic dysfunction with preserved ejection fraction
aortic insufficiency can be the result of
ascending aortic aneurysm
myocardial hypertrophy
Syphilitic/Luetic aortitis can lead to
aortic insufficiency
most common cause of rheumatic valvulitis is
mitral stenosis
what process is dominant in mitral stenosis
Fibrosis NOT calcification
“fish mouth” deformity of which valve is classic
mitral valve stenosis
Aschoff nodules are present where?
in mitral valve acute rheumatic valvulitis
most common cause of mitral regurgitation is
myxomatous mitral valve disease - associated with prolapse
in mitral regurg there is increased ground substance deposition where?
middle layer of the leaflets - spongiosa
associates with marfan
acute Mitral regurg can be the result of
papillary muscle rupture
ischemic Mitral regurg is worse with what type of MI
- Inferior wall MI of the left ventricle
emboli from valve endocarditis can result in
Lung thrombi
infarcted bowel
stroke
gangrene
3 things that can cause non-bacterial thrombotic endocarditis
- mucin secreting cancers
- hypercoagulable state
- Collagen vascular disease
2 complications of prosthetic valvles
- thrombosis
- pannus overgrowth - fibrosis
