Valvular Heart Disease: Aortic and Mitral Flashcards
As stenosis develops:
Resistance to flow ____
Pressure must ____ to maintain flow
If pressure cannot be ____, then flow will ____
increase
increase
increased; decrease
Compensatory Mechanisms for Valve Stenosis include?
Hypertrophic remodeling
Increased contractility
As regurgitation develops:
Flow of blood will occur towards the area of?
Hemodynamic consequences depend on?
least resistance
chamber compliance
Valve Regurgitation Compensatory mechanisms include?
Chamber dilation to increase compliance and decrease pressure
Increase total stroke volume in order to maintain forward stroke volume
Consequences of Valve Dysfunction
Chamber remodeling results in?
enlargement and hypertrophy
Consequences of Valve Dysfunction
Pressure Overload occurs from which valve dysfunction?
Causes what type of hypertrophy?
Pulmonic Stenosis and Aortic Stenosis
Concentric ventricular hypertrophy
Consequences of Valve Dysfunction
Volume overload occurs from which valve dysfunction?
Causes what type of hypertrophy?
Tricuspid Regurgitation and Mitral Regurgitation
Eccentric Ventricular Hypertrophy
Consequences of Valve Dysfunction
Cardiac ____
Pulmonary ____
Clinical symptoms of?
fibrosis
hypertension
heart failure
Bicuspid Aortic Valve occurs in what % of the population?
These patients are more prone to?
This condition is associated w/?
1-2%
endocarditis
aortopathy and coarctation
Aortic Stenosis Symptoms
Heart failure
SOB/DOE
D/t diastolic dysfunction from hypertrophied LV there is increased pulmonary venous pressure; eventually leading to systolic dysfunction
Aortic Stenosis Symptoms
Angina
Increased LVEDP & Decreased coronary perfusion pressure in setting of LVH leads to subendocardial ischemia,
Concomitant CAD
Aortic Stenosis Symptoms
Occurs due to decreased blood flow to brain?
Syncope
Aortic Stenosis PE
Asymmetric BP in young patients could suggest?
Pulsus tardus et parvus means?
Coarctation w/ a bicuspid valve
Delayed/weak carotid upstroke
Aotric Stenosis PE
Auscultation:
Systolic murmur where?
Murmur intensity correlates w/?
Gallavardin phenomenon is when?
Soft or absent S2 sounds occurs when?
at base radiating to neck
severity
dissociation of the harsh and musical components of murmur
severe
Aortic Stenosis - Diagnostic Testing
Echocardiogram:
Transthoracic shows?
Transesophageal shows?
AVA, Pressure gradients, leflet number, LV function, LVH, Pulmonary HTN
Clarify leaflet number, measure aortic dimension
Aortic Stenosis - Diagnostic Testing
EKG shows?
LVH
LAE
may develop Afib
Aortic Stenosis - Diagnostic Testing
Lab work to collect?
BNP
Aortic Stenosis - Diagnostic Testing
Cardiac Cath shows?
evaluate CAD & hemodynamics
Aortic Stenosis Treatment
Indications for surgery
Severe AS w/ Symptoms
Severe AS w/ EF < 50%
Severe AS undergoing another cardiac surgery
Aortic Stenosis Treatment
Medical Therapy
No medical therapy specifically for AS
Treat concomitant HTN, CAD, Afib
Less invasive option for AVR is?
TAVR - Transcatheter Aortic Valve Replacement
Acute AR - Presentation
Hx includes
Dissection
Endocarditis
Severe dyspnea
Respiratory distress
Acute AR - Presentation
PE includes
Pulmonary Edema
LV heave w/ hyperdynamic precordium
Soft diastolic murmur at left lower sternal border; may not be audible
Physical signs of endocarditis or dissection
Chronic AR - Presentation
Hx includes
Symptoms will depend on LV function
DOE, fatigue, HF
Chronic AR - Presentation
PE includes
Wide pulse pressure
Diastolic decrescendo murmur heard best at left lower sternal border at end-expiration (severity is inversely proportional to duration)
Systolic murmur due to increased flow
AR diagnostic testing
Echocardiogram
Transthoracic shows?
Transesophageal shows?
Severity of AR, leaflet number, LV function, LV chamber dimensions
Clarify leaflet number, measure aortic dimension, dissection, endocarditis