Heart Failure Flashcards
Risk Factors for developing HF
HTN
DM
Metabolic Syndrome
Atherosclerotic dz
Metabolic Syndrome is when the patient has any 3 of the following
Abdominal adiposity
Hypertriglyceridemia
Low HDL
HTN
Fasting Hyperglycemia
Etiology of HF can be from?
Valvular dz
Cardiomyopathy
HTN
Ischemic Heart Dz - major cause of HFrEF
Pathophysiology of HF
Increased LVEDP d/t structural or functional impairment of ventricular filling or ejection of blood leads to?
Activation of SNS, RAAS, increased ADH
Pathophysiology of HF
Activation of SNS, RAAS, increased ADH leads to?
Vasoconstriction/increased blood volume
Pathophysiology of HF
Vasoconstriction/increased blood volume leads to?
Increased preload & afterload
Pathophysiology of HF
Increased preload & afterload leads to?
Decreased SV & congestion
Pathophysiology of HF
Decreased SV & congestion leads to?
Increased LVEDP d/t structural or functional impairment of ventricular filling or ejection of blood
RAAS activation
Renin secreted to low renal perfusion pressure leads to?
Cleaving of angiotensinogen to angiotensin I to II via ACE
RAAS activation
Cleaving of angiotensinogen to angiotensin I to II via ACE leads to?
Vasoconstriction, increased ADH & aldosterone secretion
RAAS activation
Vasoconstriction, increased ADH & aldosterone secretion leads to
Increased Na, H20 retention
RAAS activation
Increased Na, H20 retention leads to?
Increased preload, afterload, pressures in heart
RAAS activation
Increased preload, afterload, pressures in heart leads to?
cardiac remodeling, hypertrophy, sympathetic activity
RAAS activation
cardiac remodeling, hypertrophy, sympathetic activity leads to?
Renin secreted in response to low renal perfusion pressure
Diagnosis of HF
Assessment includes?
Clinical Hx
Physical examination
ECG, labs
Diagnosis of HF
Labs
NT-proBNP > 125 pg/mL
BNP >/= 35 pg/mL
Diagnosis of HF
Imaging?
TEE
Diagnosis of HF
HF Diagnosis Confirmed
Determine cause and classify
HFrEF is?
HFmrEF is?
HFpEF is?
LVEF </= 40%
LVEF 41-49%
LVEF >/= 50%
In pts w/ HF what should be assessed at each encounter to guide overall management including adjustment of what?
vital signs and evidence of clinical congestion
diuretics and other medications
In pts w/ symptomatic HF, clinical factors indicating the presence of what? should be sought via the what?
advanced HF
Hx and Physical Exam