Valvular Heart Disease Flashcards

1
Q

Characteristic symptoms of valvular heart disease?

A

EXERTIONAL symptoms are characteristic; at rest, valve issues can be asymptomatic:
Breathlessness
Chest pain
Collapse/dizzy spells

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2
Q

Describe cardiac related breathlessness

A

Usually related to exertion and is often associated with ankle swelling

Patients describe orthopnoea and PND - ask how many pillows they sleep with?
Patients describe sitting up as relieving symptoms - this relieves venous congestion (effect of gravity)

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3
Q

Which type of heart failure are orthopnoea and PND associated with?

A

Left-sided heart failure (has effects on lungs)

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4
Q

New York Heart Association Functional Classification (NYHA)?

A

Class I - no limitation (but do have heart disease)

Class II - slight limitation of ordinary activity, on marked exertion

Class III - marked limitation of less than ordinary activity, e.g: on minimal activity

Class IV - severe limitation of minimal activity or symptoms at rest

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5
Q

Signs of right-sided heart failure?

A

Raised JVP

Ankle/sacral pitting oedema - venous congestion changes hydrostatic pressure in capillaries

Hepatic congestion - liver is vulnerable to circulatory disturbances so right-sided heart failure causes this

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6
Q

Apex beat in mitral stenosis?

A

Tapping apex

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7
Q

Apex beat in left ventricular dilatation?

A

There is volume overload and a displaced and diffuse apex

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8
Q

Apex beat in left ventricular hypertrophy?

A

There is pressure overload and a displaced and heaving apex

Sometimes, the apex is be displaced. Heaves may be felt though

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9
Q

When do parasternal heaves occur?

A

Thrusting feeling

When there is right ventricular overload due to COR PULMONALE (right-sided heart failure secondary to pulmonary hypertension and lung disease)

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10
Q

What is a cardiac murmur?

A

Audible turbulence of blood flow

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11
Q

Types of cardiac murmurs?

A

Innocent and pathological

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12
Q

Important information when describing murmurs?

A

Systolic or diastolic murmur?

What type of murmur?

Where is it loudest?

Where does it radiate to?

What grade of murmur?

Is the murmur influenced by breathing?

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13
Q

Differentiating between systolic and diastolic murmurs?

A

Feel carotids:
Systolic murmurs occur after S1 and are in time with the pulse

Diastolic murmurs occur after S2 and will not be in time with the pulse

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14
Q

Types of systolic murmurs?

A

Pansystolic - heard at a constant volume throughout systole

Ejection systolic - increase in volume towards S2 before dropping off

ADD PICTURE

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15
Q

Types of diastolic murmurs?

A

Early diastolic - decrease in volume towards S1

Mid-diastolic (rumbling) - variable volume towards S1 (increase, decrease, increase in volume)

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16
Q

Where do murmurs commonly radiate to?

A

Carotids (aortic stenosis)

Axilla (mitral regurgitation)

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17
Q

Grading system of murmurs?

A
I - very quiet
II - quiet but easy to heart
III - loud
IV - loud with a thrill
V - very loud with a thrill
VI - loud and audible without a stethoscope
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18
Q

How does inspiration affects murmurs?

A

Right-sided murmurs tend to be louder with inspiration

19
Q

When are systolic clicks heard?

A

Mitral valve prolapse (two valve flaps do not close evenly)

20
Q

When is a continuous murmur heard?

A

Ventricular-septal defect (can occur post-MI)

21
Q

When is a pericardial rub heard?

A

Heard throughout the cycle and indicates pericarditis (swelling of pericardial sac)

22
Q

Features of innocent (functional) murmurs?

A

Soft (less than 3/6 severity)

Position-dependent (these murmurs tend to be influenced by venous return so position changes are important)

Often early systolic murmurs (diastolic murmurs are never innocent)

No thrills are felt

23
Q

What is valve stenosis?

A

Valves which do not open properly, e.g: aortic stenosis (most common valve lesion)

24
Q

What is valve regurgitation?

A

Valves which do not close properly

25
What is mixed valve disease?
Valves which neither open properly nor close properly - mixture of stenosis and regurgitation
26
Causes of aortic stenosis?
Degenerative (age-related) due to calcification Congenital, e.g: a common abnormality is the aortic bicuspid valve (should have 3 cusps) Rheumatic
27
3 symptoms of aortic stenosis?
Breathlessness Chest pain - coronary arteries are above aortic valve so coronary perfusion is affected Dizziness/syncope
28
3 signs on examination of aortic stenosis?
Low volume pulse - not enough blood being pumped into systemic circulation Forceful displaced apex - left ventricular hypertrophy (tall QRS complexes on ECG) Ejection systolic murmur that can radiate to carotids
29
Treatment of aortic stenosis?
Conventional valve replacement - very successful; mostly normal life span if there is no left ventricular hypertrophy Trans-catheter aortic valve replacement (TAVI) - crush valve with stent-balloon Balloon aortic valvotomy (BAV) -
30
Types of prosthetic heart valves and facts?
Mechanical - longevity is an advantage and tend to be used in younger patients; will be on life-long warfarin Bio-prosthetic - normally last 10 years and tend to be used in older patients; no warfarin is required
31
Valve replacement vs TAVI?
Valve replacement is still preferred due to good long-term outcomes, there are no contra-indications and a CABG can be done at the same time (all patients will have a coronary angiograph beforehand) TAVI - tends to be used in those with co-morbidites and if they have had a previous sternotomy
32
Causes of mitral regurgitation, separated into broad categories?
``` Leaflets: Prolapse (can be congenital or due to chordae rupture) Rheumatic (immune complex deposition) Myxomatous (floppy leaflets) Endocarditis ``` Chordae rupture (tends to be degenerative and age-related) - prolapse/flail leaflet Papillary muscle rupture - ischaemic Annular (ring attached mitral valve) dilatation - functional (there is poor leaflet apposition)
33
Symptoms of mitral regurgitation?
Breathlessness Pulmonary oedema Fatigue
34
Examination signs of mitral regurgitation?
Displaced apex Pansystolic murmur that radiate to the axilla Cardiomegaly on CXR
35
Treatment of mitral regurgitation using medication, surgery, etc?
Medications - diuretics (for functional mitral regurgitation with heart failure); also, ACEIs Surgical: Repair - only an option for mitral valve prolapse Replacement Percutaneous - clips in infancy are showing encourgaing results so far
36
Causes of mitral stenosis?
Essentially, RHEUMATIC is the main cause | Rare causes include congenital
37
Symptoms of mitral stenosis?
Breathlessness Fatigue Palpitation (AF) - many patients with mitral stenosis will get AF due to left atrial hypertrophy
38
Examination signs of mitral stenosis?
Malar flush - sign of advanced disease Tapping apex beat Mid-diastolic rumbling; a diastolic murmur that is LOCALISED at the apex Straight left heart border on CXR
39
Treatment of mitral stenosis with medication, surgery, etc?
Medication - diuretics and treat AF Surgery - valve replacement Balloon valvuloplasty
40
Causes of aortic regurgitation?
Leaflets: Endocarditis Connective tissue diseases Rheumatic Annulus: Marfans (disease of connective tissue) Aortic dissection
41
Symptoms of aortic regurgitation?
Breathlessness
42
Examination signs of aortic regurgitation?
Collapsing pulse Displaced apex Early diastolic murmur at the left sternal edge (tricuspid area) - best heart with patient sitting up and holding an exhalation Cardiomegaly on CXR
43
Treatment of aortic regurgitation with medication, surgery, etc?
Medications - ACEIs (for dilated left ventricle) Surgery - to deal with symptoms and LV dilatation; options include valve replacement