Valvular Heart Disease Flashcards
Has valvular heart disease incidence increased or decreased over time?
decreased
When a normal valve is open, the pressure on either side of the valve is effectively equal so there is not a significant pressure gradient across the open valve. T or F?
true
What is normal flow through a valve called?
laminar or parabolic flow
The circulatory system is made up of independent “hoses”, therefore a kink in one hose will not effect the workings of another. T or F?
false
Stenotic valves can cause what in the circulatory system?
loss of laminar flow, areas of turbulent flow, pressure/volume overload
Stenotic valve leads to:
pressure overload, turbulent flow, and hypertrophy
Regurgitant valve leads to:
volume overload, turbulent flow, and dilation
Doppler above the baseline represents flow (away from, towards) transducer?
towards
What is a narrowing, thickening, fusion, or blockage of a valve that impedes or obstructs blood flow through the valve?
Valvular stenosis
What are the three levels of impact of valvular stenosis?
proximal, at the level of the stenosis, and distal
(Proximal, distal, at the level of) the stenotic valve, blood backs up and pressure increases.
proximal
Pressure overload pattern is present in what chamber to the stenotic valve?
proximal chamber
Pressure overload pattern is also known as what?
increased afterload
(Hypertrophy, dilation) in the proximal chamber is a result of a stenotic valve.
hypertrophy
When atrioventricular valves are stenotic, atria cannot compensate for increased pressure and volume, therefore they enlarge. T or F?
true
At the level of the stenotic valve, the stenotic leaflets experience what during the open phase?
doming
Valvular area (increases, decreases) within the valve orifice in a stenotic valve.
decreases
What causes doming in a stenotic valve?
increase in pressure in the proximal chamber pushes on the undersurface of the leaflets
If a valve’s orifice area decreases, what happens to velocity?
increases in attempt to maintain cardiac output
Distal to the stenotic valve, flow is ________ and pressure ________.
turbulent, decreases
What is the first imaging technique to locate and evaluate a stenotic valve?
TTE with doppler
What is pressure half time?
the time required for the peak gradient across the valve to reduce to one-half
What is calculated via the P1/2T equation?
MVA and TVA
What is a mean pressure gradient?
averages the instantaneous gradients across the open valve
What is calculated via the continuity equation?
AVA and PVA
What is the maximum pressure gradient?
peak instantaneous gradients across an open valve
What is another name for valvular regurgitation?
insufficiency
What is classified as primary (organic) regurgitation?
structural changes to the valve itself causes regurgitation
What is classified as functional (secondary) regurgitation?
regurgitation caused by chamber remodeling (changes to the atria/ventricles)
What is the vena contracta?
high velocity laminar flow within the narrowest portion of the regurgitant jet
What does a MS murmur sound like?
low-pitched, diastolic rumble with opening snap
2 main causes of mitral stenosis are:
rheumatic fever, severe mitral annular calcification
Follow the chain reaction of mitral stenosis:
MS—increased in LAP—MV leaflet doming—LAE—backup and enlargement of Pul.Veins—increased PAP—PHTN—increased RA and RV pressure—etc.
2 associations of MS:
mitral regurgitation due to LAE and dilated annulus, prohibiting leaflet closure, LA thrombus due to LAE and swirling of blood
2 complications of MS:
increased risk of infective endocarditis
decreased cardiac output
5 Echo findings of MS:
diastolic doming of anterior mitral valve leaflet, MV leaflet thickening, decreased MVA (<4cm^2), anterior motion of the posterior mitral valve leaflet, LAE
2 M-mode findings of MS:
decreased MV excursion, anterior motion of the posterior mitral valve leaflet
3 Echo findings of PH resulting from MS:
flattened IVS, small, D-shaped LV in diastole and systole
MV Pressure Half Time Equation:
MVA = 220 / P(1/2)T
MS severity:
mild: >1.5, severe: <1.0
What is the most common primary valve disease?
aortic stenosis
3 Etiologies of AS:
calcific AS
congenital bicuspid AS
rheumatic AS
What is the most common etiology of AS in the US?
calcific AS
What is the most common etiology of AS worldwide?
rheumatic AS
What does the AS murmur sound like?
systolic crescendo decrescendo, heard at sternal border, radiates to carotids
Two complications of AS:
LV pressure overload leads to LV hypertrophy
increase risk of infective endocarditis
Continuity Equation:
AVA= (VTI(LVOT)) X (CSA(LVOT)) / VTI(AOV)
Aortic stenosis severity:
mild: >1.5cm^2
severe:<1.0cm^2
What are two causes of acute AR?
ascending aortic dissection
infective endocarditis
What are two causes of chronic AR?
Aortic stenosis
bicuspid AOV
What does the AR murmur sound like?
high-pitched, blowing, diastolic decrescendo at left sternal border
What is an Austin Flint murmur?
severe AR murmur, sounds like low-pitched rumble at apex
Complications of AR:
overtime, LV dilation
decreased LV function
heart failure
AR echo findings:
diastolic flutter of anterior mitral valve leaflet
left ventricular dilation which may lead to hypertrophy
What does the TS murmur sound like?
diastolic rumble varies with respiration and has opening snap
3 causes of TS:
rheumatic heart disease
Ebstein anomaly
RA thrombus/tumor
TS echo findings:
thickened leaflets
diastolic doming
RA enlargement
TVA equation:
190 / P(1/2)T
What does the TR murmur sound like?
holosystolic that increases with inspiration
3 causes of TR:
secondary TR due to RA/RV enlargement
myxomatous degeneration primary TR
Complications of TR:
RA/RV enlargement leads to A-fib
enlarged IVC
Echo findings of TR:
RA enlargement
dilated IVC
diastolic flutter of TV leaflets
RVSP equation:
RVSP= 4V^2 + RAP
PH severity:
normal: 10-25 mmHg
severe: >70 mmHg
What does the PS murmur sound like?
harsh systolic ejection heard at left upper sternal border
3 levels of PS:
subvalvular/infundibular
valvular
supravalvular
Causes of PS:
congenital
carcinoid heart disease
PS Echo findings:
thickening of leaflets
RV hypertrophy
flattened IVS
D-shaped LV
What does the PR murmur sound like?
low-pitched diastolic murmur increased with inspiration
What is a Graham-Steele Murmur?
TR murmur heard when PH is present
high-pitched blowing diastolic murmur
PR causes:
PH causes annular dilation
infective endocarditis/vegetation