Valvular Heart Disease Flashcards
SVC & IVC
-Brings blood back to the heart
Pulmonary Artery
only artery that has venous blood
-goes to lungs to receive oxygen
Pulmonary Vein
- bring back to LA
- oxygenated blood
LV
- Pushes blood to aorta to the rest of body
- oxygenated blood
- work horse of the heart
Atrioventricular valves
between atria and ventricles
- Tricuspid & mitral
- S1 created w/ closure
Semiulnar
- Aortic & pulmonic
- S2 w/ closure
- in ventricular outflow tracts
Aortic Valve
- Calcified and degenerates
- Most common to have issues over time
- 3 leaflet valve
S1
softer than S2 at the base; often louder at apex
S2
normal splitting of S2 with inspiration; disappears with expiration; may be normal in younger, healthy patients & children
S3
gallop; heard just after S2; ”Kentucky” or lub- dub-ta; due to extra fluid striking a compliant left ventricle
S4
heard just before S1; “Tennessee” or ta-lub-dub; associated with a thickened ventricle (hypertension) or aortic stenosis
Regurgitation or Insufficiency
benign or pathological
-Backward flow
Stenosis
- narrowing or impedence in flow
- Always pathological
Systole
-occurs between S1 & S2; feel with pulse Innocent & Physiologic murmurs Aortic stenosis Mitral Regurgitation Tricuspid Regurgitation Pulmonary Stenosis Hypertrophic Cardiomyopathy
Diastole
(always pathological) – occurs after S2 before S1
Mitral Stenosis
Aortic Regurgitation
Common Systolic murmurs: Aortic Stenosis
- Aortic stenosis (most common of aging)
- Harsh murmur
- Right, 2nd ICS
- Crescendo-decrescendo (diamond shaped)
- Intensity correlates with severity of obstruction
- Carotid upstroke may be decreased and/or delayed (parvus tardus)
Aortic Stenosis
Causes:
Aging- Degenerative calcification of aortic cusps
Congenital- Bicuspid Aortic Valve (BAV)
Rheumatic Heart Disease (RHD)
Risk Factors
Elevated LDL & lipoprotein a, DM, smoking, CKD, metabolic syndrome
Aortic Stenosis Symptoms
- Usually no symptoms until disease is severe
- Onset age 60-80s in chronic degenerative AS
- Onset age 40-50s in BAV
- Fatigue, DOE most common
- —Triad: Angina, Heart Failure, exertional Syncope for critical AS
Management of AS
- Treat heart failure with diuretics
- Treat LV dysfunction
- Cautious use of nitrates and Ace inhibitors in Severe AS
- Avoid strenuous activity when AS is moderate or greater (esp. weight lifting)
- Aortic Valve Replacement (SAVR)
- Transcutaneous Aortic Valve Replacement (TAVR)
Common systolic murmurs: Mitral Regurgitation
- Mitral valve leaflets don’t meet, allowing backflow of blood into atrium during systole in LA
- Holosystolic
- Apex
- High-pitched; blowing
- Intensity is related to pressure gradient across the valve from left atrium to left ventricle
- May radiate to axilla or into back as gradient worsens
- Intensity increases with hand grip
- Happening in systole not as harsh as AS
MR
Acute Causes
- Acute Myocardial Infarction (with papillary muscle rupture)
- Ruptured chordae tendineae
- Infective Endocarditis
- Chest trauma
Chronic causes
-RHD; MVP; calcification; congenital; HOCM; dilated CMP
MR Symptoms
Acute
-pulmonary edema
Chronic
-fatigue, DOE, orthopnea (late symptoms)
MR management
Treat heart failure with diuretics
Treat LV dysfunction
If Atrial Fibrillation, anticoagulation needed
Follow serial echocardiograms based on progression of disease and symptoms
Timing of surgical repair
MitraClip percutaneous device for severe inoperable MR
Mitral Valve Prolapse
Heard best at the apex
Systolic “click” murmur
May be followed by high-pitched late systolic crescendo-decrescendo murmur at apex
Most common in women ages 15-30 years old
Causes:
unknown
may be genetic; often associated with Marfan’s Syndrome or other connective tissue disorders