Vaccines- Quiz 2

Question 1

Attenuated vs Inactivated

Answer 1

Attenuated: “Modified-Live” give more broad, longer lived immunity than inactivated.

Inactivated: “Killed”

• We don’t do live virus immunizations in the US anymore

Question 2

Key Notes about administration

Answer 2

-Give live virus vaccines at least 28 days apart

-Reduced doses should never be used

-Re-immunization is not harmful

-Space vaccines at least 1 inch apart

-Be aware of and monitor for adverse reactions and respond appropriately

Question 3

Inactivated Vaccine Examples

Answer 3

-Diphtheria, tetanus, pertussis (DTaP & Tdap)
-Pna
-Meningitis
-Hep A
-Hep B
-Polio (rest of the world uses attenuated)

Question 4

Contraindications for Inactivated Vaccines

Answer 4

-Anaphylaxis to prior dose

-Allergy to Neomycin, polymyxin B, streptomycin

-Allergy to yeast-> No Hep B or Inactive Polio

-Can’t have a moderate or severe infection for HPV or Hib (H. flu B)

Question 5

Contraindications for Live Attenuated Vaccines

Answer 5

-Immunocompromised
–HIV
–Chemo
–Prednisone >20mg/day
–IVIG therapy

Question 6

Live Attenuated Vaccine examples

Answer 6

-Baccilus Calmette-Guerin (TB) normally not used in the US
-Measles, Mumps, Rubella, Varicella
-Rotavirus

Question 7

What is the vaccine recommended for EACH pregnancy around 27-36 weeks?

Answer 7

Tdap

Maximizes the transfer of antibody from mother to baby

Doesn’t matter when last vaccination was given