Vaccines- Johns Flashcards
Live attenuated vaccine
live microbes are weakened by growing them for many generations in animals or tissue cultures
Ex: oral polio, MMR, zoster
*be careful giving them to immunosuprressed and pregnant women
Which vaccine type should you NOT give to an immunocompromised patient?
LIVE ATTENUATED***
Inactivated vaccine
whole organisms that have been killed
stimulate immune system but do not cause disease
** polio, influenza, hep A
Subunit vaccines
Use only part of the bacterium or virus
Ex: Typhoid, hep B, pertussis, meningitis
Conjugate vaccines
Link proteins or sugars an organism to a macromolecule that is known to be immunogenic (so your immune system learns to attack the attached molecule?)
allows babies immune system to recognize bacteria
Ex. Hib, pneumoccus
Inactivated toxins
Some bacteria cause disease by producing toxins, inactivated toxins are used to prevent disease
Ex: tetanus, diptheria
Edible Vaccines
Genetically engineered potatoes, bananas and tomatoes
When eaten, will initiate an immune response against harmful intestinal bacteria and virus
Plantibodies
specific antibodies made in palnts
What are valid contraindications to vaccination?
Anaphylactic reaction Prior high fever Immunodeficiency Pregnancy ( but can still get flu shot) Significant acute illness
What are NOT valid contraindications to vaccinations?
Minor illness Mild/moderate local rxn or fever antimicrobial therapy Dz exposure Pregnancy in household Premature birth Breast feeding Allergies to products not in vaccines Family hx
Who should not recieve the influneza vaccine?
Anaphylactic hypersensitivity to eggs
Allergy to thimerosol
History of Guillain-Barre Syndrome
Acute febrile conditions