Vaccines Dr. Robinson EXAM 4

Question 1

What is primary and secondary Immunodeficiency?

Answer 1

Congenital (genes)
-X-linked agammaglobulinemia
-Severe Combined Immunodeficiency (SCID)
-Chronic granulomatous diseas

Question 2

What is secondary Immunodeficiency?

Answer 2

Acquired
-HIV infection
-Hematopoietic malignancies
-Immunosuppressive Drugs
-Radiation/Chemotherapy
-Glucocorticoids
-Chronic disease
-Diabetes, COPD, congenital heart disease, sickle cell disease

Question 3

What HIV CD4 count indicates high-level immunosuppression?

Answer 3

<200 cells/mm

<15 infants & children

Question 4

What dose of Prednisone indicates high-level immunosuppression?

Answer 4

Prednisone equivalent > 20 mg/day for 2 weeks

-Corticosteroid use (< 20 mg/day) ≥ 2 week is low-level immunosuppression

Question 5

Pregnancy is a natural state
of immunosuppression. T/F

Answer 5

False

the state of pregnancy is described as immunomodulation

Question 9

What are the Live Vaccines?

Question 11

What does COVID-19 protect patients from?

Answer 11

protects from severe illness, hospitalization and death

-not from the infection

Question 12

How many COVID-19 vaccine doses are needed for immunocompromised patients over age 6?

Answer 12

at least 2 doses of the 2024-2025 COVID-19 vaccine 6 months apart

Question 16

Which influenza vaccine can not be given….
Why?

Answer 16

…. (intranasal)

because it is a live vaccinee

Question 19

Know resources

Answer 19

Check Live vaccines: FDA
PneumoRecs VaxAdvisor

Answer 20

Know Basic Principles slide
she provides information on the case