Vaccines Flashcards
Weakened or inactivated
Live attenuated vaccine (MoA)
Killed whole organism
Inactivated
Non-living pathogen (MoA)
The Influenza vaccine is an …. vaccine
Inactivated… Its killed and virus antigen purified
MoA: A vesicle is taken from the native gram-negative strain in their natural conformation.. the suitable antigens are present for vaccination. Which vaccine?
Outer membrane vesicle vaccine
A protein conjugate is attached to a bacteria polysaccharide inducing better recognition by the immune system. MoA for what vaccine?
Subtype: Protein-Polysaccharide conjugate
A virus without a genom.. MoA for which vaccine?
Subtype: Virus-like particle
Purpose of vaccines
To limit the spread of infectious diseases and protect those who canoot be vaccinated
What is herd immunity
Is population scale immunity and is achieved when a critical level of people has been vaccinated
Ag presenting vaccines arae best suited for
cancer
Not suitable for influenza virus. The inactivated influenza virus vaccine is changed every year because the envelope proteins are continually changing
Outer membrane vesicle vaccines are best suited for
Bacterial infections
Which vaccine does not have material from the actual pathogen
mRNA and DNA vaccines
HIV, Influenza, Zica and ebola, etc. are several future aspects for which vaccine technology
mRNA vaccines
Name three profound advantage for mRNA vaccines
flexible: mRNA can easily be changed if the pathogen changes
specific: as is encodes for the exact sequence of pathogen ag
efficient: it is easy to upscale production
One major disadvantage for mRNA vaccines
very unstable and needs unbroken cold chain storage
Name a disadvantage for cancer therapeutic vaccine
they do not target the underlying cause of cancer
