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Immuno - BOARDS > Vaccination > Flashcards

Vaccination Flashcards

1
Q

What is a LIVE attenuated vaccine?

A

One in which the microorganism loses its pathogenicity but retains capacity for transient growth within inoculated host

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2
Q

What type of host response does a live attenuated vaccine produce?

A

Mainly induces a CELLULAR response

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3
Q

What are some examples of live attenuated vaccines?

A

Measles, mumps, polio (sabin), rubella, varicella, yellow fever

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4
Q

What is a killed (inactivated) vaccine?

A

One in which the pathogen is inactivated by heat or chemicals - maintaining epitope structure on surface antigen is important for immune response.

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5
Q

What type of host response does a killed (inactivated) vaccine produce?

A

Humoral immunity is induced

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6
Q

What are some examples of killed vaccines?

A

Cholera, influenza, hepA, polio (salk), rabies

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7
Q

What is a con for inactivated vaccines?

A

Weaker immune response - so booster shots are usually required

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Immuno - BOARDS (7 decks)

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