HLA Subtypes - Disease Associations Flashcards
1
Q
A3
A
Hemochromatosis
2
Q
B27
A
‘PAIR’
Psoriasis, Ankylosing spondylitis, Inflammatory bowel disease, Reiter’s syndrome
3
Q
B8
A
Graves disease
4
Q
DR2
A
Multiple sclerosis
Hay fever
SLE
Goodpasture’s
5
Q
DR3
A
DM1 and Grave’s disease
6
Q
DR4
A
RA, DM1
7
Q
DR5
A
Pernicious anemia (B12 deficiency), hashimoto’s thyroiditis
8
Q
DR7
A
Steroid-responsive nephrotic syndrome
9
Q
Hemochromatosis
A
A3
10
Q
Psoriasis
A
B27
11
Q
Ankylosing spondylitis
A
B27
12
Q
IBD
A
B27
13
Q
Reiter’s syndrome
A
B27
14
Q
MS
A
DR2
15
Q
Hayfever
A
DR2
16
Q
SLE
A
DR2
17
Q
Goodpasture’s
A
DR2
18
Q
RA
A
DR4
19
Q
DM1
A
DR3 and DR4
20
Q
Pernicious anemia
A
DR5
21
Q
Steroid responsive nephrotic syndrome
A
DR7
22
Q
HLA associated with MHC I?
A
HLA-A, HLA-B, HLA-C
23
Q
HLA associated with MHC II?
A
HLA-DR, HLA-DP, HLA-DQ
24
Q
Grave’s disease
A
HLA-B8 and DR3