HLA Subtypes - Disease Associations Flashcards

1
Q

A3

A

Hemochromatosis

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2
Q

B27

A

‘PAIR’

Psoriasis, Ankylosing spondylitis, Inflammatory bowel disease, Reiter’s syndrome

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3
Q

B8

A

Graves disease

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4
Q

DR2

A

Multiple sclerosis
Hay fever
SLE
Goodpasture’s

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5
Q

DR3

A

DM1 and Grave’s disease

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6
Q

DR4

A

RA, DM1

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7
Q

DR5

A

Pernicious anemia (B12 deficiency), hashimoto’s thyroiditis

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8
Q

DR7

A

Steroid-responsive nephrotic syndrome

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9
Q

Hemochromatosis

A

A3

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10
Q

Psoriasis

A

B27

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11
Q

Ankylosing spondylitis

A

B27

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12
Q

IBD

A

B27

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13
Q

Reiter’s syndrome

A

B27

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14
Q

MS

A

DR2

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15
Q

Hayfever

A

DR2

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16
Q

SLE

A

DR2

17
Q

Goodpasture’s

A

DR2

18
Q

RA

A

DR4

19
Q

DM1

A

DR3 and DR4

20
Q

Pernicious anemia

A

DR5

21
Q

Steroid responsive nephrotic syndrome

A

DR7

22
Q

HLA associated with MHC I?

A

HLA-A, HLA-B, HLA-C

23
Q

HLA associated with MHC II?

A

HLA-DR, HLA-DP, HLA-DQ

24
Q

Grave’s disease

A

HLA-B8 and DR3