Cell Surface Proteins

Question 1

What cell surface proteins are found on T-cells?

Answer 1

TCR (binds antigen-MHC complex)
CD3 (associated with TCR for signal trnsdctn)
CD28 (binds B7 on APC)
CD4 (helper T-cells)
CD8 (cytotoxic T-cells)

Question 2

What cell surface proteins are found on B-cells?

Answer 2

Ig (binds antigen)
CD19, CD20, CD21(receptor for EBV), CD40
MHCII, B7

Question 3

What cell surface proteins are found on macrophages?

Answer 3

CD14, CD40
MHCII, B7
Fc and C3b receptors (enhanced phagocytosis)

Question 4

What cell surface proteins are found on NK cells?

Answer 4

CD 16 (binds Fc of IgG), CD56 (unique marker for NK)