Vaccination Flashcards
Def
Intentional administration of a harmless of less harmful form of a pathogen in order to induce a specific adaptive immune response;
Protects individuals against later exposure to the pathogen due to pdtn of memory cells;
No development of diseases symptoms
Provides?
Artificially acquired active immunity;
Immune response is activated artificially;
Introducing antigens into body to initiate pri immune response
Describe what happen after vaccination
Introduced specific diseases;
Weakened or killed pathogens;
Characteristic surface antigen of pathogen still retained;
->immunogenic effect;
Recognized by specific B lymphocytes;
Clonal expansion, mitosis;
Either
- Memory cells;
- Antibody-secreting plasma cells
How vaccination prevents diseases
Memory cells recognized surface antigen of pathogen;
Rapid clinal expansion;
Develop antibody secreting plasma cells;
Px antibodies;
Bind and inactivate virulent pathogen
Two types of vaccines
- Subunit vaccine
2. Whole-agent
3 benefits?
- Complete eradication
- Protect individuals against diseases;
- Herd immunity
Explain herd immunity
Population is immune to an infectious agent;
Transmission is prevented due to low chance of a susceptible individual contacting an infected individual
3 risks?
- Reversion of virulence to cause disease;
- Side effect; diff illness;
- Excessive vaccination reduces effectiveness of the immune system to respond to new infections