Vaccination Flashcards

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1
Q

Def

A

Intentional administration of a harmless of less harmful form of a pathogen in order to induce a specific adaptive immune response;

Protects individuals against later exposure to the pathogen due to pdtn of memory cells;

No development of diseases symptoms

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2
Q

Provides?

A

Artificially acquired active immunity;

Immune response is activated artificially;

Introducing antigens into body to initiate pri immune response

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3
Q

Describe what happen after vaccination

A

Introduced specific diseases;

Weakened or killed pathogens;

Characteristic surface antigen of pathogen still retained;
->immunogenic effect;

Recognized by specific B lymphocytes;

Clonal expansion, mitosis;

Either

  1. Memory cells;
  2. Antibody-secreting plasma cells
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4
Q

How vaccination prevents diseases

A

Memory cells recognized surface antigen of pathogen;

Rapid clinal expansion;

Develop antibody secreting plasma cells;

Px antibodies;

Bind and inactivate virulent pathogen

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5
Q

Two types of vaccines

A
  1. Subunit vaccine

2. Whole-agent

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6
Q

3 benefits?

A
  1. Complete eradication
  2. Protect individuals against diseases;
  3. Herd immunity
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7
Q

Explain herd immunity

A

Population is immune to an infectious agent;

Transmission is prevented due to low chance of a susceptible individual contacting an infected individual

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8
Q

3 risks?

A
  1. Reversion of virulence to cause disease;
  2. Side effect; diff illness;
  3. Excessive vaccination reduces effectiveness of the immune system to respond to new infections
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