Antigen Presenting Flashcards
1
Q
What is antigen presenting?
A
Display of peptides bound to membrane proteins (MHC)
2
Q
Why is antigen presentation necessary?
A
Specific recognition and activation
=> to function in immune response
3
Q
How does APC works?
A
APC engulf pathogens by phagocytosis
-> process antigens from pathogen into short peptides
-> peptides bind to MHC protein inside WR
=> protein-MHC complex
->as a vesicles, transport to CSM of APC
=> antigens ready for presentation to native Tcells
4
Q
What happen after activation of native T cells?
A
-clonal expansion;
-differentiation into effector T cells
=> function in adaptive immune response
5
Q
When will clonal expansion occurs?
A
Single cell stimulated to undergo proliferation;
Px large no of genetically identical Daughter cells
