Uveitis and systemic diseases of the eye Flashcards
How can you classify uveitis
iritis
Cyclitis
Choroiditis
Iridocyclitis
Anterior vs intermediate vs posterior
Non granulomatous and granulomatous
What is uveitis usually associated with?
Sero negative artheropathies - HLA B27 associated conditions
Which Th cells are associated with uveitis
Th 1 - Autoimmune
Th 2 - Infectious
Name some HLA alleles in uveitis
A29 - Birdshot
B51 - Behcets
B27 - anterior uveitis
What is the classic triad for uveitis
Pain
Photophobia
Blurring vision
May have irregular pupil
What are classic signs?
Keratic precipitates and mutton fat precipitates
Cell and flare - SUN criteria
What is synechiae
Adhesions seen in uveitis - you can get uveitic glaucoma
What iris nodules can you see?
Koeppe nodules -
Bussaccaa nodules - Granulomatous uveitis (TB or sarcoid)
How to treat?
Cycloplegics to reduce adhesions and reduced pressure
Anti-inflamm
What can you see on the retina in intermediate uveitis
You will have painless blurry vision
Snow banking and snow balls
What symptoms set posterior uveitis apart?
Photopsia and dyschromatopsia
What is the usual cause?
Infectious > Autoimmune
What can you see on fundoscopy
Pizza pie appearance, (CMV retinitis) pearly beads (candida), light in the fog (toxoplasmosis), sarcoidosis (punched out lesions)
CMV retinitis and toxoplasmosis can be transferred from mum to bebe
Why is HLA B 27 important in anterior uveitis?
As it is associated with IBD, psoriasis, ank spon, reactive arthiritis
How do you remember ank spon
The A’s
