Uveitis Flashcards

1
Q

Anatomical classification of uveitis

A

Anterior (iris+ pars plicata) iridocyclitis
Intermediate (para plana) para planitis
Posterior (choroiditis)
Panuveitis (all 3 parts)

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2
Q

Pathological classification of uveitis

A

Granulomatous and non-granulomatous

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3
Q

D shaped pupil in

A

Iridocyclitis

Due to disinsertion of iris due to weakening of roof of iris

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4
Q

Anterior uveitis clinical features

A
Pain 
Redness
Photophobia 
Blepharospasm
Discharge (watery)
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5
Q

Examination findings in anterior uveitis

Just the names briefly

A
Keratin precipitates 
Aqueous cells
Aqueous flare
Muddy iris 
Bussaca and koeppe’s nodules 
Miosis
Post synechae - secclusio and occlusio pupillae
Festooned shaped pupil 
Peripheral anterior synechae 

Iris bombe

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6
Q

What is arlt’s triangle

A

KPs are maximum in lower part of cornea

Due to convection current in aqueous humour

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7
Q

Why does miosis happen in uveitis

A

Due to release of toxins from inflamed tissue

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8
Q

What kind of pupil in angle closure glaucoma

A

Mid dilated pupil

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9
Q

Uveitis pupil shape

A

Constricted pupil

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10
Q

TOC of anterior uveitis

A

Topical steroids

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11
Q

Role of cyclopegics in anterior uveitis

A

Relieves pain and gives rest to the inflamed tissue
Prevents posterior synechae
Break posterior synechae
Relieves spasm (better blood supply and better healing,gives rest to ciliary muscles)

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12
Q

Which drug is ONLY a mydriatic

A

Phenylephrine

Active mydriasis

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13
Q

Strongest mydriatic

A

Atropine

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14
Q

Luminate program

A

Non-steroidal treatment of uveitis

Voclosporin

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15
Q

Intermediate uveitis

A

Inflammation of vitreous and peripheral retina along with para plana

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16
Q

Etiology of intermediate uveitis

A

Idiopathic (more than 70%)
Infective – TB, Leprosy, syphilis
Non-infective-sarcoidosis,Multiple sclerosis

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17
Q

Clinical features of intermediate uveitis

A

Blurred vision

Painless floaters

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18
Q

Examination findings of Intermediate uveitis

A
Decreased visual acuity
Retrolental flare
few KP
Snowballs
Snow banking – fibro vascular and exudative plaque (pathognomic)
Periphlebitis (hallmark)
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19
Q

Most complication of pars planitis

A

Cystoid macular edema

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20
Q

Step ladder approach for intermediate uveitis

A

Local steroids
Systemic steroids
Immunosuppressive drugs
Para plana vitrectony

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21
Q

Posterior uveitis features

A
Choroiditis-round yellow patches 
Vitritis-haziness and flare 
Papillitis-inflammatory optic neuritis
CME
Retinal edema
Periphlebitis
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22
Q

Some causes of non-granulomatous anterior uveitis

A

Ankylosis spondylitis
Psoriatic arthritis
Reuter’s syndrome
JRA-juvenile rheumatoid arthritis

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23
Q

Reiter’s syndrome

A

Arthritis
Conjunctivitis
Urethritis

24
Q

Still’s disease

A

Systemic onset JRA (16 yrs)

25
Q

What is white uveitis

A

Atypical anterior uveitis (5 features of uveitis absent)

Occurs in early onset pauciarticular seronegative JRA associated with uveitis

26
Q

Complications of JRA

A

Complicated cataract
Secondary glaucoma
Band shaped keratopathy

27
Q

Candle wax dripping present in

A

Venous sheathing

Occurs in sarcoidosis

28
Q

Ocular features of sarcoidosis

A

Sarcoidosis nodules (episclera/sclera)
Interstitial keratitis
Band shaped keratopathy
Granulomatous panuveitis

29
Q

What is Behçet’s disease

A

Obliterative vasculitis due to circulating immune complexes

30
Q

Behçet’s disease genetic predisposition

A

HLA B5

HLA B51

31
Q

Transient hypopion syndrome seen in

A

Behçet’s disease

Non-granulomatous anterior and posterior uveitis

32
Q

Eeles disease also known as

A

Periphlebitis retinae

33
Q

Clinical features of eales disease

A
(Hypersensitivity reaction of TB antigen)
Diminution of vision/floaters
Recurrent vitreous haemorrhage 
Venous sheathing 
(Non-granulomatous posterior uveitis)
34
Q

Management of eale’s disease

A

ATT
management of vitreous haemorrhage

Partial-postural management (propped up position)
Total-pars plana vitrectomy

(Non-granulomatous posterior uveitis)

35
Q

MC ocular feature in HIV

A

HIV induced microangiopathy

  • haemorrhage
  • micro aneurysm
  • cotton wool spots
36
Q

MC opportunistic infection

A

CMV retinitis
(Sauce and cheese retinopathy)
(Pizza)

37
Q

Other opportunistic infections and what do they cause

A

Toxoplasmosis
Pneumocystis carinii
^^ choroiditis

Herpes zoster
^^ acute retinal necrosis

38
Q

HAART therapy

MC ocular side effect

A

Immune recovery uveitis

Non-granulomatous/posterior uveitis

39
Q

Headlight in fog appearance

A

Toxoplasmosis

40
Q

Treatment of toxoplasmosis

A

Clindamycin

41
Q

Syphilis fundus findings

A

Salt and pepper fundus (diffuse chorioretinitis)

Juxtapapillary choroiditis

42
Q

TB ocular manifestation

A

Granulomatous panuveitis
MC allergic manifestation of TB-phlyctenular keratoconjunctivitis
MC ocular feature of TB-uveitis

43
Q

VKH syndrome (vogt koyanagi harada)

A
Granulomatous panuveitis + systemic feature 
(Encephalitis 
Vestibular dysfunction 
Tinnitus 
Alopecia
Poliosis
Vitiligo)
44
Q

Sympathetic ophthalmitis

A

Perforating injury in one eye(exciting eye) causing uveitis in the other eye (sympathising eye)

45
Q

Etiology of sympathetic ophthalmitis

A

Autoimmune reaction towards uveal tissue

46
Q

Clinical features of sympathetic ophthalmitis

A
Granulomatous panuveitis
Dalen Fuch nodules 
Retrolental flare 
Decreased accommodation 
Photophobia
47
Q

Where is dalen fuch norules present

A

Bruchs membrane

48
Q

First sign on sympathetic ophthalmitis

A

Retrolental flare

49
Q

First symptom of sympathetic ophthalmitis

A

Decreased accommodation

Photophobia

50
Q

What is the dangerous area of eye

A

Ciliary body

Any trauma to CB is a big risk of sympathetic ophthalmitis

51
Q

Fuch’s heterochromic cyclitis type of uveitis + other features

A
Atypical  anterior uveitis 
Heterochtomia iridis (involved eye-hypochromic)
52
Q

Type of uveitis in fuch’s heterochromic cyclitis

A

Non-granulomatous anterior uveitis

53
Q

Examination findings in fuch’s heterochromic cyclitis

A

Rubeosis iridis
Stellate KP
Heterochromia iridis

54
Q

Complications of fuch’s heterochromic cyclitis

A

Complicated cataract

Secondary glaucoma

55
Q

Amslers sign

A

Present in fuch’s heterochromic uveitis

Blood in anterior chamber on paracentesis
Due to rubeosis iridis at angle of AC

56
Q

Type of uveitis and TOC of onchocerciasis

A

Non-granulomatous ant/post

TOC-Ivermectin

57
Q

Opthalmia nodosum

A

Intense granulomatous inflammation

Caterpillar hair in the eye