UTI (medicine)

Question 1

Anatomic Definitions of UTI

Answer 1

Anatomic definitions
Lower UTI:urethritis(inflammation of urthera) & cystitis(inflammation of bladder)
Upper UTI:pyelonephritis(inflammation or renal parenchyma) & prostatitis( inflammation of prostate)

Question 2

Clinical definitions of UTI

Answer 2

Uncomplicated UTI: lower UTI in immunocompetent non-pregnant woman without underlying structural or neurologic disease
Complicated UTI:
•Upper UTI in non pregnant woman
•any UTI (upper or lower) in pregnant woman
•any UTI (upper or lower) in men
•UTI with underlying structural disease or immunosuppression

Question 3

Laboratory definitions of UTI

Answer 3

Bacteriuria = presence of bacteria in urine
UTI = presence of a pure growth of >10(5) organisms per mL of fresh midstream sample urine

Question 4

Most common cause of UTI

Answer 4

E.coli

Question 5

Investigations of UTI

Answer 5

Urine dipstick/Urinalysis
Urine culture (gold standard test)
CBC
UCE
electrolytes
Blood cultures
Dna detection
Renal tract ultrasound or CT scan

Question 6

What is the gold standard investigation of UTI

Answer 6

Urine culture

Question 7

What is sterila pyuria?

Answer 7

Presence of WBCS in urine with negative urine culture <10(5) organisms

Question 8

Sterile pyuria in present in which conditions?

Answer 8

Most common renal tuberculosis
Treated UTI <2 wks prior
Inadequately treated UTI
Calculi,prostatitis
Bladder tumour, polycystic kidney,

Question 9

Lower UTI Treatment duration and best initial treatment?

Answer 9

Uncomplicated lower UTI (urethritis and cystitis) :
Best initial treatment is Trimethoprim-sulfamethoxazone(TMP-SMX)
3 days in women and 10 days in men